Measuring the Deformation of Adsorbed Particles using the Quartz Crystal Microbalance

POSTER

Abstract

We numerically simulate the hydrodynamic force on ellipsoidal particles, adsorbed on an oscillating surface. From the simulation results, we fit a relation between this force and the particle aspect ratio and the oscillation frequency. The relation is used to extract shape information from quartz crystal microbalance (QCM) measurement data of the adsorption of 70 nm liposomes, whose shape is changed by varying the osmotic pressure difference across the liposomal bilayer. We thereby determine the membrane bending energy, consistent with literature values.

*We would like to acknowledge funding support from the National Research Foundation of Singapore (NRF2015NRF-POC001-019) to N-J.C.

Presenters

  • jurriaan gillissen

    • University College London

Authors

  • jurriaan gillissen

    • University College London

  • Joshua A Jackman

    • Stanford University

  • Seyed Tabaei

    • Chalmers University

  • Bo Kyeong Yoon

    • Nanyang Technological University

  • Nam-Joon Cho

    • Nanyang Technological University