Three-Dimensional Flow Analysis of Paravalvular Leak Jet

ORAL

Abstract

The paravalvular leak (PVL) jet, which occurs through the gap between the native annulus and the outer edge of the prosthetic valve, resembles a wall jet. As the PVL jet is associated with short- and long-term mortality, a detailed investigation is required. Few studies have been conducted to quantify the PVL jet; however, they mostly overlook the three-dimensional nature of the jet. This study aims to characterize the three-dimensional features of the PVL jet. Phase-locked 3D PIV was performed in vitro at ten evenly spaced time points during diastole using a plenoptic camera. 3D printed nodules were placed between the valve and jacket to mimic PVL. The pulse duplicator was configured with three different cardiac output settings, and two different-sized nodules were used to simulate mild, moderate, and severe PVL. The presence of spanwise curvature is a distinctive feature of the PVL jet that differentiates it from a conventional wall jet. As a reason, the PVL jets are crescent-shaped. This curvature effect influences the characteristics of the PVL jet, including its morphology, spread rate, velocity decay, and trajectory, making them distinct from those of a typical wall jet. Further, characterizing the PVL jet could improve diagnostics and severity prediction.

*This research was partially supported by National Science Foundation (NSF) Award Number CBET – 2145189.

Presenters

  • Neeraj Adhikari

    • Auburn University

Authors

  • Neeraj Adhikari

    • Auburn University
  • Michele Mastrogiacomo

    • Auburn University
  • Bibek Sapkota

    • Auburn University
  • Vrishank Raghav

    • Auburn University