Networks in Protein Folding

ORAL

Abstract

We take a networks approach to protein folding by identifying different protein conformations with nodes, while an elementary step of the system (rotation around a bond) that takes one configuration to another is defined as a link. The energies of configurations are scalar quantities associated with each node. Using this approach we can show that the scale-free nature of the observed protein conformation networks can be explained by simple results obtained on gradient networks.

Authors

  • Erzs\'ebet Ravasz Regan

    Beth Israel Deaconess Medical Center, Harvard Medical School

  • Zolt\'an Toroczkai

    University of Notre Dame, Physics Department

  • G. Gnanakaran

    Los Alamos National Laboratory, T-10