Glassiness in RNA folding

COFFEE_KLATCH · Invited

Abstract

We study secondary structures of random RNA molecules by means of a renormalized field theory based on an expansion in the sequence disorder. We show that there is a continuous phase transition from a molten phase at higher temperatures to a low-temperature glass phase. Based on an exact inequality, we argue that RNA conformations in the glass phase are similar to those at the transition. \\ $[1]$ M. Laessig and K.J. Wiese, The freezing of random RNA, Phys. Rev. Lett. 96 (2006), 228101. \\ $[2]$ F. David and K.J. Wiese, Systematic field theory of the RNA glass transition, q-bio.BM/0607044 (2006); accepted for publication in Phys. Rev. Lett.

Authors

  • Kay Wiese

    LPT ENS, Paris, CNRS - LPT ENS, 24 rue Lhomond, 75231 Paris, France