How Phospholipid Diffusion Depends on the Presence of Alpha-Hemolysin Pores and Adsorbed DNA

POSTER

Abstract

Building on our recent finding that the adsorption of a flexible macromolecule to a supported phospholipid bilayer produces spots of different lipid heterogeneity even in bilayers comprised of one single type of phospholipid, investigations are now reported regarding DNA and also a pore-forming protein, bacterial streptolysin. The larger question is to understand how macromolecules of bio-significance with specific macroscopic geometric structures affect phospholipid mobility.

Authors

  • Mo Jiang

    University of Illinois, Urbana-Champaign

  • Bo Wang

    University of Illinois, Urbana-Champaign, University of Illinois

  • Sung Chul Bae

    University of Illinois, Urbana-Champaign, Dept of Materials Science \& Engineering, University of Illinois at Urbana-Champaign, University of Illinois at Urbana-Champaign, University of Illinois, Dept of Materials Science \& Engineering, Univ of Illinois at Urbana-Champaign

  • Steve Granick

    Department of Materials Science and Engineering, University of Illinois, University of Illinois, Urbana-Champaign, material science and engineering, UIUC, Materials Science and Engineering, University of Illinois, Dept of Materials Science \& Engineering, University of Illinois at Urbana-Champaign, Dept. Materials Science and Engineering, University of Illinois at Urbana-Champaign, University of Illinois at Urbana-Champaign, University of Illinois, Dept of Materials Science \& Engineering, Univ of Illinois at Urbana-Champaign, Material Science and Engineering, UIUC