The Interaction of Photon Beams with the DNA Molecules: Genomic Medical Physics

I propose a novel method for the modification of the corrupted human DNA\footnote{J.D. Watson and F. H. C. Crick, \textbf{Nature}, 171, 737-738 (1953).} code that causes particular genetic disease. The method is based on the nonlinear interaction between the DNA molecule and the ``modulation photons'' generated in beat wave driven free electron laser, BW-FEL.\footnote{V. Alexander Stefan. \textbf{Beat Wave Driven Free Electron Laser} (S-U-Press, 2002, La Jolla, CA)[cf. V. Stefan, et al., \textbf{Bull.~Am. Phys. Soc.} 32, No. 9, 1713 (1987)]} The BW-FEL frequency is given by $\nu $\textbf{$\sim $}$\gamma ^{2}$n$\Omega _{e }$(\textbf{$\gamma $} is the free electron beam relativistic factor, n is the harmonic number of the electron Bernstein plasma mode, and $\Omega _{e}$ is the electron cyclotron frequency). The meV ``carrier photons'' are focused on the area of the brain, the source-center of a genetic disease. For the BW-FEL parameters: the free electron beam guiding d.c. magnetic field \textbf{$\sim$} 1kG, \textbf{$\gamma \sim $}10$^{3}$, and n=10, the keV ``modulation photons'' are generated, which are easily focused on the nucleotides. By modulating the frequency of the BW-FEL, the parametric resonance with the different DNA (sub-DNA) eigen molecular oscillation-modes are achieved, leading to the ``knock-on'' of the unwanted (corrupted) nucleotides.