Laser Stimulated Genomic Exchange in Stem Cells. Laser Non-cloning Techniques

POSTER

Abstract

I propose a novel technique for a pluripotent stem cell generation. Genomic exchange is stimulated by the beat-wave free electron laser, (B-W FEL), frequency matching with the frequencies of the DNA\footnote{J.D. Watson and F. H. C. Crick, \textit{Nature}, 171, 737-738 (1953).} eigen-oscillations. B-W FEL-1\footnote{V. Stefan, B.I.Cohen, C. Joshi\textit{ Science}, \textbf{243},4890, (Jan 27,1989); Stefan, et al., Bull. APS. 32, No. 9, 1713 (1987); Stefan, APS March-2011, {\#}S1.143; APS- March-2009, {\#}K1.276.} scans entire stem cell; B-W FEL-2 probes the chromosomes. The scanning and probing lasers: 300-500nm and 100-300nm, respectively; irradiances: the order-of-10s mW/cm$^{2}$ (above the threshold value for a particular gene structure); repetition rate of few-100s Hz. A variety of genetic-matching conditions can be arranged. Genomic glitches, (the cell nucleus transfer\footnote{Scott Noggle et al. \textit{Nature}, 478, 70-75 (06 October 2011).}), can be hedged by the use of lasers.

Authors

  • V.Alexander Stefan

    Institute for Advanced Physics Studies, Stefan University