Graphene Nanopres for DNA Fingerprinting

ORAL

Abstract

The recent progress in nanopore experiments with transverse current is important for the development of fast, accurate and cheap finger-printing techniques for single nucleotide. Despite its enormous potential for the next generation DNA sequencing technology, the presence of large noise in the temporal spectrum of transverse current remains a big challenge for getting highly accurate interpretation of data. In this paper we present our {\it abinitio} calculations, and propose graphene based device for DNA fingerprinting. We calculate transmission current through graphene for each DNA base (A,C,G,T). As shown in our work, a proper time-series analysis of a signal provides a higher quality information in identifying single bio-molecule is translocating through the nanopores.

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Authors

  • Towfiq Ahmed

    Los Alamos National Laboratory

  • Alexander V. Balatsky

    Los Alamos National Laboratory, NORDITA, Los Alamos National Lab, Los Alamos National Laboratory and Nordic Institute of Theoretical Physics (Nordita)

  • J.T. Haraldsen

    Los Alamos National Laboratory

  • Ivan K. Schuller

    Department of Physics and Center for Advanced Nanoscience, University of California-San Diego, USA, University of California San Diego, Center for Advanced Nanoscience, Department of Physics, University of California, San Diego, Department of Physics and Astronomy, University of California San Diego, 9500 Gilman Dr., San Diego, La Jolla, CA 92093, U.S.A, University of California, San Diego, University of California - San Diego

  • M. Di Ventra

    University of California, San Diego

  • K.T. Wikfeldt

    Nordic Institute of Theoretical Physics (Nordita)