Quantification of the Rupture Potential of Intracranial Saccular Aneurysms under Contact Constraints

ORAL

Abstract

The rupture predictability of intracranial aneurysms is an important medical challenge. While most intracranial aneurysms are asymptomatic, the rupture potential of both symptomatic and asymptomatic lesions is relatively unknown. Moreover, an intracranial aneurysm constrained by a nerve tissue might be a common scenario for a physician to deal with during the treatment process. In this work, we develop a computational model of an intracranial saccular aneurysm constrained by nerve tissues to investigate the protective role of constrained tissue on the aneurysm. A comparative parametric study for constraints of varying length, for aneurysms of varying neck size and aneurysm wall with varying geometric and material models are considered. Our computational results will demonstrate the influence of contact constraints on the level of stress near the fundus and provide an insight on when these constraints are protective and when they are destructive.

Presenters

  • Manjurul Alam

    Department of Bioengineering, George Mason Univ

Authors

  • Manjurul Alam

    Department of Bioengineering, George Mason Univ

  • Padmanabhan Seshaiyer

    Department of Mathematical Sciences, George Mason University