Selective response of DNA sequences at THz frequencies from numerical simulation

We numerically simulate the response of DNA sequences to driving with THz radiation using the dynamical model of Ref. [1]. Homogeneous sequences of AT base-pairs experience an amplitude response that is distinct from homogeneous GC sequences in the parameter space of driving amplitude and frequency. Heterogeneous sequences with the same number of AT and GC pairs, but different ordering, also exhibit distinct responses in some regions of parameter space. Results indicate that THz driving is selective between different DNA sequences. [1] R. Tapia-Rojo, J. J. Mazo, and F. Falo, “Thermal and mechanical properties of a DNA model with solvation barrier,” Physical Review E 82, 031916 (2010).