Excess heat capacity measurement of nano/bio-materials by photo-thermal conversion calorimetry

Photothermal therapy in medical care including cancer is gradually being valued. We modified Thermal activity monitor to measure the heat generated by the photothermal reaction of nanoparticles. The thermal Activity Monitor is a freestanding multichannel microcalorimeter. We use this system to measure the photothermal reaction excess heat and calculate the specific heat of the photothermal nanoparticles. Furthermore, We can calculate the elevated net temperature. In addition, this method can also measure the excess heat generated by various nanoparticles and proteins excited by laser at a specific wavelength. According to this result, we can accurately know the thermal reaction effect of the nanoparticles to achieve better treatment.