DNA Mechanics and Gene Expression II

Presentations

• Torsional Mechanics of Fundamental Processes

  ORAL · Invited

  March 8, 2023, 11:00 AM – March 8, 2023, 11:36 AM

  Publication: 1. T. T. Le, M. Wu, J.H. Lee, N. Bhatt, J.T. Inman, J.M. Berger, and M. D. Wang. "Etoposide Promotes DNA Loop Trapping and Barrier Formation by Topoisomerase II." Nat Chem. Bio., under revision.
  2. X. Gao, Y. Hong, F. Ye, J.T. Inman, and M.D. Wang. "Torsional Stiffness of Extended and Plectonemic DNA." Phys. Rev. Lett. 127:028101 (2021).
  3. T.T. Le, X. Gao, S. Park, J. Lee, J. T. Inman, J.H. Lee, J.L. Killian, R.P. Badman, J.M. Berger, and M.D. Wang. "Synergistic Coordination of Chromatin Torsional Mechanics and Topoisomerase Activity." Cell 179: 619–631 (2019).

  Presenters

  • Michelle D Wang

    Cornell University

  Authors

  • Michelle D Wang

    Cornell University

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• Physical Mechanisms for DNA Twist Changes and Supercoiling Induced by Salt and Temperature Changes

  ORAL

  March 8, 2023, 11:36 AM – March 8, 2023, 11:48 AM

  Publication: Chen Zhang, Fujia Tian, Ying Lu, Bing Yuan, Zhi-Jie Tan, Xing-Hua Zhang*, and Liang Dai*. "Twist-diameter coupling drives DNA twist changes with salt and temperature", Science Advances 8, eabn1384 (2022).
  
  Xiao-Wei Qiang, Chen Zhang, Hai-Long Dong, Fu-Jia Tian, Hang Fu, Ya-Jun Yang, Liang Dai*, Xing-Hua Zhang*, and Zhi-Jie Tan*. "Multivalent cations reverse the twist-stretch coupling of RNA", Physical Review Letters 128, 108103 (2022).

  Presenters

  • Liang Dai

    City Univ of Hong Kong

  Authors

  • Liang Dai

    City Univ of Hong Kong

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• Tensile force in a single-stranded DNA gap

  ORAL

  March 8, 2023, 11:48 AM – March 8, 2023, 12:00 PM

  Presenters

  • Harold D Kim

    Georgia Institute of Technology

  Authors

  • Harold D Kim

    Georgia Institute of Technology

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• Detecting Poloidal Bias In DNA Minicircles

  ORAL

  March 8, 2023, 12:00 PM – March 8, 2023, 12:12 PM

  Presenters

  • Tony Lemos

    Georgia Institute of Technology

  Authors

  • Tony Lemos

    Georgia Institute of Technology

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• Stability of DNA double helix under sharp bending

  ORAL

  March 8, 2023, 12:12 PM – March 8, 2023, 12:24 PM

  Publication: 1. Stability diagram of small DNA minicircles, M. Kim, J. S. Kim, submitted
  2. Sequence-dependent twist-bend coupling in DNA minicircles, M. Kim, S. Bae, I. Oh, J. Yoo, J. S. Kim, Nanoscale, 13, 20186 (2021)

  Presenters

  • Jun Soo Kim

    Ewha Womans University

  Authors

  • Jun Soo Kim

    Ewha Womans University

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• Multiscale modeling of chromatin: from fibers to genes to chromosomes

  ORAL · Invited

  March 8, 2023, 12:24 PM – March 8, 2023, 1:00 PM

  Presenters

  • Tamar Schlick

    New York University

  Authors

  • Tamar Schlick

    New York University

  • Zilong Li

    New York University

  • Zilong Li

    New York University

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• Understanding Transcriptional Regulation by Characterizing Gene Regulatory Functions of Synthetic Loci in Mammalian Cells

  ORAL

  March 8, 2023, 1:00 PM – March 8, 2023, 1:12 PM

  Presenters

  • Zheng Diao

    Rice University

  Authors

  • Zheng Diao

    Rice University

  • Oleg A Igoshin

    Rice Univ

  • Caleb J Bashor

    Rice University

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• A Differentiable Model of Nucleic Acid Dynamics

  ORAL

  March 8, 2023, 1:12 PM – March 8, 2023, 1:24 PM

  Presenters

  • Ryan Krueger

    Harvard University

  Authors

  • Ryan Krueger

    Harvard University

  • Megan C Engel

    University of Calgary, Harvard University

  • Michael P Brenner

    Harvard University

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• Structural and Dynamic signatures of active chromatin polymers

  ORAL

  March 8, 2023, 1:24 PM – March 8, 2023, 1:36 PM

  Presenters

  • Sumitabha Brahmachari

    Rice University

  Authors

  • Sumitabha Brahmachari

    Rice University

  • Tomer Markovich

    Rice University

  • Frederick C MacKintosh

    Rice University

  • Jose N Onuchic

    Rice University

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