Molecular Machines II

FOCUS · Q08 · ID: 1107048

Presentations

  • Millisecond Functional Dynamics of RNA Polymerases Elucidated by Markov State Models

    ORAL · Invited

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    Publication: 1. Unarta, I.S., Cao, S., Kubo, S., Wang, W., Cheung, P.P.H., Gao, X., Takada, S., Huang, X., "Role of Bacterial RNA Polymerase Gate Opening Dynamics in DNA Loading and Antibiotics Inhibition Elucidated by quasi-Markov State Model", Proc. Nat. Acad. Sci. U.S.A., 118(17), e2024324118, (2021)

    2. Tse K.M., Xu, J., Xu, L., Sheong, F.K., Wang, S., Chow, H.Y., Gao, X., Li, X., Cheung, P.P., Wang, D.*, Zhang, Y., Huang, X., "Intrinsic Cleavage of RNA Polymerase II Adopts a Nucleobase-independent Mechanism Assisted by Transcript Phosphate", Nature Catalysis, 2, 228-235, (2019)

    3. Da, L., Pardo, F. , Xu, L., Silva, D. , Zhang, L. , Gao, X., Wang, D., Huang, X., "Bridge Helix Bending Promotes RNA Polymerase II Backtracking Through a Critical and Conserved Threonine Residue", Nature Communications, 7, 11244, (2016)

    Presenters

    • Xuhui Huang

      University of Wisconsin-Madison

    Authors

    • Xuhui Huang

      University of Wisconsin-Madison

    View abstract →

  • Speed variations of bacterial replisomes

    ORAL

    –

    Publication: Bhat, D., Hauf, S., Plessy, C., Yokobayashi, Y. and Pigolotti, S., 2022. Speed variations of bacterial replisomes. Elife, 11, p.e75884.

    Presenters

    • Simone Pigolotti

      Okinawa Institute of Science & Technolog

    Authors

    • Simone Pigolotti

      Okinawa Institute of Science & Technolog

    • Deepak Bhat

      Okinawa Institute of Science & Technology

    • Samuel Hauf

      Okinawa Institute of Science and Technology

    • Charles Plessy

      Okinawa Institute of Science and Technology

    • Yohei Yokobayashi

      Okinawa Institute of Science and Technology

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  • DBIO Thesis Prize Winner: Jonathon L. YulyElectron bifurcation and correlations in biological energy transduction

    ORAL · Invited

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    Publication: Yuly, J. L., Zhang, P., Lubner, C. E., Peters, J. W., & Beratan, D. N. (2020). Proceedings of the National Academy of Sciences, 117(35), 21045-21051.
    Yuly, J. L., Zhang, P., Ru, X., Terai, K., Singh, N., & Beratan, D. N. (2021). Chem, 7(7), 1870-1886.
    Yuly, J.L., Zhang, P., and Beratan, D.N. (2021). Current Opinion in Electrochemistry, 29, 100767.
    Terai, K., Yuly, J.L., Zhang, P., and Beratan, D.N. (2022). Proceedings of the National Academy of Sciences, Submitted.

    Presenters

    • Jonathon L Yuly

      Princeton University

    Authors

    • Jonathon L Yuly

      Princeton University

    • Peng Zhang

      Duke University

    • Kiriko Terai

      Duke University

    • David N Beratan

      Duke University

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  • Speedy synthetic DNA motors are on a roll

    ORAL · Invited

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    Publication: "Chemical-to-mechanical molecular computation using DNA-based motors with onboard logic" Selma Piranej, Alisina Bazrafshan & Khalid Salaita; Nature Nanotechnology volume 17, pages514–523 (2022)
    "Adhesive Dynamics Simulations of Highly Polyvalent DNA Motors" Aaron T. Blanchard, Selma Piranej, Victor Pan, and Khalid Salaita J. Phys. Chem. B 2022, 126, 39, 7495–7509
    "DNA Gold Nanoparticle Motors Demonstrate Processive Motion with Bursts of Speed Up to 50 nm Per Second"Alisina Bazrafshan, Maria-Eleni Kyriazi, Brandon Alexander Holt, Wenxiao Deng, Selma Piranej, Hanquan Su, Yuesong Hu, Afaf H. El-Sagheer, Tom Brown, Gabriel A. Kwong, Antonios G. Kanaras, and Khalid Salaita, ACS Nano, vol. 15 (5), pg. 8427–8438

    Presenters

    • Khalid Salaita

      Emory University

    Authors

    • Khalid Salaita

      Emory University

    • Selma Piranej

      Emory University

    View abstract →