Synthetic Biology

Presentations

• Continuous evolution of dynamic, multi-state, and computational protein functionalities

  ORAL · Invited

  March 4, 2024, 9:00 AM – March 4, 2024, 9:36 AM

  Presenters

  • Vojislav Gligorovski

    Ecole Polytechnique Federale de Lausanne

  Authors

  • Vojislav Gligorovski

    Ecole Polytechnique Federale de Lausanne

  • Sahand J Rahi

    Ecole Polytechnique Federale de Lausanne

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• Unveiling Heterogeneity in Optogenetic Circuit Dynamics via Single-Cell Time-Lapse Imaging

  ORAL

  March 4, 2024, 9:36 AM – March 4, 2024, 9:48 AM

  Presenters

  • Joshua Azukas

    Stony Brook University (SUNY)

  Authors

  • Joshua Azukas

    Stony Brook University (SUNY)

  • Rafal Krzyszton

    Stony Brook University

  • Gabor Balazsi

    Stony Brook University (SUNY)

  • Helmut H Strey

    Stony Brook University (SUNY)

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• Efficient design of stochastic molecular circuits with differentiable programming

  ORAL

  March 4, 2024, 9:48 AM – March 4, 2024, 10:00 AM

  Presenters

  • Francesco Mottes

    Harvard University

  Authors

  • Francesco Mottes

    Harvard University

  • Ramya Deshpande

    Harvard University

  • Michael P Brenner

    Harvard University

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• Construction of a stably integrated mammalian toggle switch from bacterial components

  ORAL

  March 4, 2024, 10:00 AM – March 4, 2024, 10:12 AM

  Presenters

  • Julia Petreczky

    Stony Brook University (SUNY)

  Authors

  • Julia Petreczky

    Stony Brook University (SUNY)

  • Rafal Krzyszton

    Stony Brook University

  • Kai Wahlin

    Stony Brook University

  • Yiming Wan

    Stony Brook University

  • Gabor Balazsi

    Stony Brook University (SUNY)

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• Unraveling Transcriptional Dynamics in Mammalian Cells using a Synthetic Reporter

  ORAL

  March 4, 2024, 10:12 AM – March 4, 2024, 10:24 AM

  Presenters

  • Zheng Diao

    Rice University

  Authors

  • Zheng Diao

    Rice University

  • Oleg A Igoshin

    Rice Univ

  • Caleb J Bashor

    Rice University

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• Adaptive DNA amplification of synthetic gene circuit opens new way to overcome cancer chemoresistance

  ORAL

  March 4, 2024, 10:24 AM – March 4, 2024, 10:36 AM

  Publication: Y.M. Wan*, Q.H. Mu*, R. Krzysztoń, J.Cohen, D. Coraci, C. Helenek, A. Lin, K.S. Farquhar, J.G. Wang, G. Balazsi. Adaptive DNA amplification of synthetic gene circuit opens new way to overcome cancer chemoresistance. PNAS, (in press) (*equal contribution).

  Presenters

  • Yiming Wan

    Stony Brook University

  Authors

  • Yiming Wan

    Stony Brook University

  • Quanhua Mu

    The Hong Kong University of Science and Technology

  • Rafal Krzyszton

    Stony Brook University

  • Joseph Cohen

    Stony Brook University (SUNY)

  • Damiano Coraci

    Stony Brook University

  • Christopher Helenek

    Stony Brook University

  • Christopher Tompkins

    KromaTid, Inc

  • Annie Lin

    Stony Brook University

  • Kevin Farquhar

    PONCE Therapeutics, Inc.

  • Erin Cross

    KromaTid, Inc.

  • Jiguang Wang

    The Hong Kong University of Science and Technology

  • Gabor Balazsi

    Stony Brook University (SUNY)

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• Non-disruptive characterization of cell-free synthesized membrane interacting-proteins with a quartz microbalance

  ORAL

  March 4, 2024, 10:36 AM – March 4, 2024, 10:48 AM

  Presenters

  • Aset Khakimzhan

    University of Minnesota

  Authors

  • Aset Khakimzhan

    University of Minnesota

  • Ziane Izri

    Univerisity of Minnesota

  • Seth Thompson

    University of Minnesota

  • Oleg Dmytrenko

    Helmholtz Institute for RNA-based Infection Research (HIRI)

  • Chase L Beisel

    Helmholtz Institute for RNA-based Infection Research (HIRI)

  • Vincent Noireaux

    University of Minnesota

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• Flexible PEG-LifeAct Crosslinkers Tune Actin Network Structure and Mechanics in a Contour Length Dependent Manner

  ORAL

  March 4, 2024, 10:48 AM – March 4, 2024, 11:00 AM

  Presenters

  • Tyler D Jorgenson

    University of Chicago

  Authors

  • Tyler D Jorgenson

    University of Chicago

  • Kashmeera D Baboolall

    University of Chicago

  • Cristian Suarez

    University of Chicago

  • David R Kovar

    University of Chicago

  • Margaret L Gardel

    University of Chicago

  • Stuart J Rowan

    University of Chicago, university of chicago

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• Abstract Withdrawn

  ORAL Withdrawn

  March 4, 2024, 11:00 AM – March 4, 2024, 11:12 AM

  View abstract →

• Microeconomics of Metabolism: A Linear Response Theory of Evolved Metabolic Systems

  ORAL

  March 4, 2024, 11:12 AM – March 4, 2024, 11:24 AM

  Publication: Yamagishi, J. F., & Hatakeyama, T. S. (2023). Linear Response Theory of Evolved Metabolic Systems. Physical Review Letters, 131(2), 028401.

  Presenters

  • Jumpei F Yamagishi

    The University of Tokyo

  Authors

  • Jumpei F Yamagishi

    The University of Tokyo

  • Tetsuhiro S Hatakeyama

    Earth Life Science Institute (ELSI), Tokyo Institute of Technology

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• Enzyme Diffusion Watched in Real Time Directly

  ORAL

  March 4, 2024, 11:24 AM – March 4, 2024, 11:36 AM

  Presenters

  • Qi Pan

    Department of Polymer Science and Engineering, University of Massachusetts, Amherst

  Authors

  • Qi Pan

    Department of Polymer Science and Engineering, University of Massachusetts, Amherst

  • Steve Granick

    Department of Polymer Science and Engineering, University of Massachusetts, Amherst

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