Using electric fields to control brain activity

Neural oscillations reflect and organize brain functions. Brain Stimulation methods such as Transcranial Alternating Current stimulation (TACS) and Transcranial Magnetic Stimulation (TMS) use electric fields to control brain activity. In this talk I will present our recent research on TACS/TMS mechanisms and how to develop more effective stimulation protocols using concurrent brain measurements. I will show how non-invasive brain stimulation affects neural activity at the level of local field potentials and single-unit activity. I will demonstrate how local electric fields will affect spiking behavior and how this is affected by neuron morphology and orientation to the electric field. I will further discuss how findings from animal experiments can be translated to improve human brain stimulation protocols based on careful modeling and mapping of stimulation parameters. I will discuss how tracking brain oscillations in real-time to inform stimulation timing can improve the effectiveness of brain stimulation.