Adaptive networks: erosion of microfluidic channels
ORAL
Abstract
Microfluidics has enabled major advances in biology, where it has allowed to study and explore microscopic flows as they happen in biological systems. However, such microfluidic devices often fail to mimic a key aspect of living systems: their adaptability to incoming flows.
Here, we make a first step towards adaptive microfluidic networks by working with hydrogels (PEG-NB, polyethylene glycol norbornene) that erode in the presence of a flow of chemical. From the quantitative experimental data gathered, we show the erosion and absorption laws of the system, and develop consistent numerical simulation. Those allow us to easily explore the parameters space, and find adequate conditions to homogenize the flows in random networks. This homogenization is essential in biological systems to enhance the exchanges happening constantly at the interfaces.
Here, we make a first step towards adaptive microfluidic networks by working with hydrogels (PEG-NB, polyethylene glycol norbornene) that erode in the presence of a flow of chemical. From the quantitative experimental data gathered, we show the erosion and absorption laws of the system, and develop consistent numerical simulation. Those allow us to easily explore the parameters space, and find adequate conditions to homogenize the flows in random networks. This homogenization is essential in biological systems to enhance the exchanges happening constantly at the interfaces.
* This work benefited from the funding of the French Agence Nationale de la Recherche (ANR), under grant ANR-21-CE30-0044, and the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under grant AL 1429/5-1 (DFG).
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Presenters
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Julien Bouvard
Institut Polytechnique de Paris
Authors
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Julien Bouvard
Institut Polytechnique de Paris
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Swarnavo Basu
TU Munich
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Charlott Leu
LMU Munich
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Onurcan Bektas
LMU Munich
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Joachim Rädler
LMU Munich
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Karen Alim
TU Munich
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Gabriel Amselem
Institut Polytechnique de Paris