Biomolecular Condensates in the Cell Nucleus

Presentations

• Condensates in Chromatin Organization and Cancer

  ORAL · Invited

  March 6, 2024, 12:30 PM – March 6, 2024, 1:06 PM

  Publication: https://www.biorxiv.org/content/10.1101/2023.02.27.530281v1

  Presenters

  • Amy Strom

    Princeton University

  Authors

  • Amy Strom

    Princeton University

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• Imaging transcription condensates in three dimensional genomes

  ORAL · Invited

  March 6, 2024, 1:06 PM – March 6, 2024, 1:42 PM

  Publication: Hao, S., Fuehrer, H., Flores, E., Demmerle, J., Lippincott-Schwartz, J., Liu, Z., Sukenik, S., and Cai, D. (2022). YAP condensates are highly organized hubs for YAP/TEAD transcription. bioRxiv, 2022.2010.2024.513621.

  Presenters

  • Danfeng Cai

    Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University

  Authors

  • Danfeng Cai

    Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University

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• The ripening dynamics of nuclear biomolecular condensates

  ORAL

  March 6, 2024, 1:42 PM – March 6, 2024, 1:54 PM

  Presenters

  • Tafadzwa Chigumira

    Carnegie Mellon University

  Authors

  • Tafadzwa Chigumira

    Carnegie Mellon University

  • Deb S Banerjee

    Carnegie Mellon University, The University of Chicago

  • Rachel M Lackner

    University of Pennsylvania

  • Josiah Kratz

    Carnegie Mellon University

  • David M Chenoweth

    University of Pennsylvannia

  • Shiladitya Banerjee

    Carnegie Mellon University

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• Condensate-mediated chromatin organization through elastocapillary interactions

  ORAL

  March 6, 2024, 1:54 PM – March 6, 2024, 2:06 PM

  Presenters

  • Hongbo Zhao

    Princeton University

  Authors

  • Hongbo Zhao

    Princeton University

  • Amy Strom

    Princeton University

  • Jorine Eeftens

    Princeton University

  • Natalia Orlovsky

    Princeton University

  • Mikko Haataja

    Princeton University

  • Cliff Brangwynne

    Princeton University

  • Andrej Kosmrlj

    Princeton University

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• Transcription factor clusters as information transfer agents

  ORAL

  March 6, 2024, 2:06 PM – March 6, 2024, 2:18 PM

  Presenters

  • Rahul Munshi

    Princeton University

  Authors

  • Rahul Munshi

    Princeton University

  • Sergey Ryabichko

    Princeton University

  • Michal Levo

    Princeton University

  • Eric F Wieschaus

    Princeton University

  • Thomas Gregor

    Princeton University

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• Genomic clustered pattern of transcription factor binding reflects phase-separated transcriptional condensates

  ORAL

  March 6, 2024, 2:18 PM – March 6, 2024, 2:30 PM

  Presenters

  • Chongzhi Zang

    University of Virginia

  Authors

  • Chongzhi Zang

    University of Virginia

  • Zhenjia Wang

    University of Virginia

  • Shengyuan Wang

    University of Virginia

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• The transcription factor TEAD1 forms repressive biomolecular condensates in renal cell carcinomas

  ORAL

  March 6, 2024, 2:30 PM – March 6, 2024, 2:42 PM

  Presenters

  • Jindayi Liang

    Johns Hopkins Bloomberg School of Public Health

  Authors

  • Jindayi Liang

    Johns Hopkins Bloomberg School of Public Health

  • Danfeng Cai

    Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University

  • Justin Demmerle

    Georgetown University

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• Chromatin Heterogeneity Modulates Nuclear Phase Behavior and Condensates Dynamics

  ORAL

  March 6, 2024, 2:42 PM – March 6, 2024, 2:54 PM

  Presenters

  • Jing Xia

    Princeton University

  Authors

  • Jing Xia

    Princeton University

  • Cliff Brangwynne

    Princeton University

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• Spatial Organization of Regulatory Chromatin At Transcription Condensates

  ORAL

  March 6, 2024, 2:54 PM – March 6, 2024, 3:06 PM

  Presenters

  • Jan-Hendrik Spille

    University of Illinois at Chicago

  Authors

  • Jan-Hendrik Spille

    University of Illinois at Chicago

  • Ganesh Pandey

    University of Illinois at Chicago

  • Jonah Galeota-Sprung

    University of Illinois at Chicago

  • Filmon Medhanie

    University of Illinois at Chicago

  • Alisha Budhathoki

    University of Illinois at Chicago

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• Mechanisms of sensitive and selective nucleation of chromatin-associated biomolecular condensates

  ORAL

  March 6, 2024, 3:06 PM – March 6, 2024, 3:18 PM

  Presenters

  • Yury A Polyachenko

    Princeton University

  Authors

  • Yury A Polyachenko

    Princeton University

  • Hans-Frederick Watanabe

    Princeton University

  • William M Jacobs

    Princeton University

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• Role of electrostatics and phase separation in regulation of gene expression in Escherichia Coli

  ORAL

  March 6, 2024, 3:18 PM – March 6, 2024, 3:30 PM

  Presenters

  • Vishal Sankar Sivasankar

    University of Missouri, Columbia, University of Missouri

  Authors

  • Vishal Sankar Sivasankar

    University of Missouri, Columbia, University of Missouri

  • Gesse A Roure

    University of Missouri

  • Roseanna N Zia

    University of Missouri-Columbia, University of Missouri

  View abstract →