Physics, History, and Future of MRI

INVITED · S43 · ID: 1851803

Presentations

  • The Endless Capabilities of Magnetic Resonance, from Zero to High Fields

    ORAL · Invited

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    Publication: 1) Kobayashi N, Parkinson B, Idiyatullin D, et al. Development and validation of 3D MP-SSFP to enable MRI in inhomogeneous magnetic fields. Magn. Reson. Med. 2021;85:831-844. doi:10.1002/mrm.28469
    2) Mullen M, Garwood M. Contemporary approaches to high-field magnetic resonance imaging with large field inhomogeneity. Prog. Nuc. Magn. Reson. Spectroscopy 2020;120-121:95-108. doi:10.1016/j.pnmrs.2020.07.003
    3) Theilenberg S, Shang Y, Ghazouani J, et al. Design and realization of a multi-coil array for B0 field control in a compact 1.5T head-only MRI scanner. Magn. Reson. Med. 2023;90(3):1228-1241. doi:10.1002/mrm.29692
    4) Tang X, Suddarth S, Qian, G, Garwood, M. Ultra-low frequency EPR using longitudinal detection and fictitious-field modulation. J Magn Reson 2020, 321, 106855. doi.org/10.1016/j.jmr.2020.106855.

    Presenters

    • Michael Garwood

    Authors

    • Michael Garwood

    View abstract →

  • Quantitative MRI and the Aging Brain

    ORAL · Invited

    –

    Publication: Bouhrara M., Reiter D.A., and Spencer, R.G. Bayesian Analysis of Transverse Signal Decay with Application to Human Brain. Magnetic Resonance in Medicine 74(3):785-802, 2015. (PMC ID # 4366365).

    Bouhrara, M., Reiter, D.A., Celik H., Fishbein, K.W., Kijowski R., and Spencer R.G. Analysis of mcDESPOT- and CPMG-derived Parameter Estimates for Two-component Non-exchanging Systems. Magnetic Resonance in Medicine 75:2406–2420, 2016. (PMC ID # 5958911).

    Bouhrara, M. and Spencer, R.G. Improved Determination of the Myelin Water Fraction in Human Brain using Magnetic Resonance Imaging through Bayesian Analysis of mcDESPOT. NeuroImage, 127(15), 456-471, 2016. (PMC ID # 4854306).

    Bouhrara M. and Spencer R. G. Rapid Simultaneous High-resolution Mapping of Myelin Water Fraction and Relaxation Times in Human Brain using BMC-mcDESPOT. NeuroImage 147:800-811, 2017. (PMC ID # 5303643).

    Bouhrara, M., Reiter D.A., Sexton K.W., Bergeron C.M., Zukley L.M., and Spencer R.G. Clinical high-resolution mapping of the proteoglycan-bound water fraction in articular cartilage of the human knee joint. Magnetic Resonance Imaging (43):1-5, 2017. (PMC ID # 5632579).

    Bouhrara M., Reiter D.A., Bergeron C.M., Zukley L.M., Ferrucci L., Resnick, S.M., and Spencer R.G. Evidence of demyelination in mild cognitive impairment and dementia using a direct and specific magnetic resonance imaging measure of myelin content. Alzheimer's and Dementia 14(8):998-1004, 2018. (PMC ID # 6097903).

    Bouhrara M., Rejimon A.C., Cortina L.E., Khattar N., Bergeron C.M., Ferrucci L., Resnick S.M., and Spencer R.G. Adult brain aging investigated using BMC-mcDESPOT based myelin water fraction imaging. Neurobiology of Aging 85:131-139, 2019. (PMC ID # 6924176).

    Bouhraha M., Cortina L.E., Rejimon A.C., Khattar N., Bergeron C., Bergeron J., Melvin D., Zukley L., and Spencer R.G. Quantitative age-dependent differences in human brainstem myelination assessed using high-resolution magnetic resonance mapping. NeuroImage 206:1-10, 2020. (PMC ID # 6981041).

    Spencer R. and Bi C. A Tutorial Introduction to Inverse Problems in Magnetic Resonance. NMR in Biomedicine. 2020; 33:e4315. https://doi.org/10.1002/nbm.4315, (PMC Pending).

    Bouhrara M., Alisch J.S.R., Khattar N., Kim R.W., Rejimon A.C., Cortina L.E., Qian W., Ferrucci L., Resnick S.M. and Spencer R.G. Association of cerebral blood flow with myelin content in cognitively unimpaired adults. BMJ Neurology Open 2(1):e000053, 2020; doi: 10.1136/bmjno-2020-000053. (PMC ID # 7903181)

    Bouhrara M., Khattar N., Elango P., Resnick S.M., Ferrucci L., and Spencer R.G. Evidence of association between obesity and lower cerebral myelin content in cognitively unimpaired adults. International Journal of Obesity 45(4):850-859, 2021. (PMC ID # 8009848)

    Bouhrara M., Cortina L.E., Khattar N., Rejimon A.C., Ajuma A., Cezayirli D., and Spencer R.G. Maturation and degeneration of the human brainstem across the adult lifespan. Aging 13(11):14862-14891, 2021. (PMCID# 822134)

    Bi C., Fishbein K., Bouhrara M., Spencer R.G. Stabilization of parameter estimates from multiexponential decay through extension into higher dimensions. Scientific Reports, 12(1):5773, 2022 (PMCID# 8986819)

    Rozowski M., Palumbo J. Bouhrara M., Bi C., Czaja W., and Spencer R.G. Input Layer Regularization of a Neural Network for Parameter Estimation. Rapid Communication, Magnetic Resonance in Chemistry 60(11): 1076-1086, 2022. (PMCID# 35593385)

    Bi C., Ou M.Y., Bouhrara M., and Spencer R.G. Span of regularization for solution of inverse problems with application to magnetic resonance relaxometry of the brain. Scientific Reports 12(1):20194, 2022 (PMCID# 9684479)

    Presenters

    • Richard G Spencer

      National Institute on Aging/National Institutes of Health

    Authors

    • Richard G Spencer

      National Institute on Aging/National Institutes of Health

    View abstract →