Does \textit{Helicobacter pylori} exhibit corkscrew motion while swimming?

POSTER

Abstract

\textit{Helicobacter pylori} is a spiral shaped bacterium associated with ulcers, gastric cancer, gastritis among other diseases. In order to colonize the harsh acidic environment of the stomach \textit{H. pylori} has to go across the gastric mucus layer. Many studies have been conducted on the swimming of \textit{H. pylori} however none have studied the trajectory path. We present a single cell experimental study of the effects of body shape in the swimming trajectory of \textit{H. pylori} in pig gastric mucin and liquid media by a quantitative analysis of the bacterium rotation and translation using phase contrast microscopy and particle tracking techniques while simultaneously measuring the bacterium body parameters. Our measurements show very well defined helical trajectories, from which we measure the body rotation.

Authors

  • Maira Constantino

    Boston University

  • Joseph Hardcastle

    Boston University

  • Rama Bansil

    Boston University