Physical Forces in Wound Healing and Regeneration

Presentations

• Topological Defects and their Role in Hydra Morphogenesis

  ORAL · Invited

  March 17, 2025, 11:30 AM – March 17, 2025, 12:06 PM

  Publication: Yonit Maroudas-Sacks, S Suganthan, Yael Ascoli-Abbina, Liora Garion, Ariel Westfried, Noam Dori, Iris Pasvinter Marko Popovic, Kinneret Keren, Mechanical strain focusing at topological defect sites in regenerating Hydra, accepted to Development (2024).
  https://www.biorxiv.org/content/10.1101/2024.06.13.598802v1.full

  Presenters

  • Kinneret Keren

    • Technion - Israel Institute of Technology
    • Technion

  Authors

  • Kinneret Keren

    • Technion - Israel Institute of Technology
    • Technion

  View abstract →

• A mechano-chemical model of Hydra regeneration

  ORAL

  March 17, 2025, 12:06 PM – March 17, 2025, 12:18 PM

  Publication: 1) Mechanical strain focusing at topological defect sites in regenerating Hydra
  Yonit Maroudas-Sacks, S. Suganthan, Liora Garion, Yael Ascoli-Abbina, Ariel Westfried, Noam Dori, Iris Pasvinter, Marko Popović, Kinneret Keren, bioRxiv 2024.06.13.598802; doi: https://doi.org/10.1101/2024.06.13.598802
  2) Confinement modulates axial patterning in regenerating Hydra,
  Yonit Maroudas-Sacks, Liora Garion, S. Suganthan, Marko Popović, and Kinneret Keren, PRX Life (Accepted)

  Presenters

  • Suganthan Senthilkumar

    • Max Planck Institute for the Physics of Complex Systems

  Authors

  • Suganthan Senthilkumar

    • Max Planck Institute for the Physics of Complex Systems

  • Yonit Maroudas-Sacks

    • Technion - Israel Institute of Technolog

  • Kinneret Keren

    • Technion - Israel Institute of Technology
    • Technion

  • Marko Popovic

    • Max Planck Institute for Physics of Complex Systems

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• Mechanically-driven closure of extreme membrane wounds in a single cell

  ORAL

  March 17, 2025, 12:18 PM – March 17, 2025, 12:30 PM

  Presenters

  • Sindy K Tang,

    • Stanford University

  Authors

  • Sindy K Tang,

    • Stanford University

  • Kevin S Zhang

    • Stanford University

  • Ambika V Nadkarni

    • Stanford University

  • Wallace F Marshall

    • UC San Francisco
    • UCSF
    • University of California, San Francisco

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• The role of cytoskeletal mechanics in wound healing in the single-celled organism Stentor coeruleus

  ORAL

  March 17, 2025, 12:30 PM – March 17, 2025, 12:42 PM

  Presenters

  • Aravind Rao Karanam

    • Rochester Institute of Technology
    • University of California, San Diego

  Authors

  • Aravind Rao Karanam

    • Rochester Institute of Technology
    • University of California, San Diego

  • Soumik Mitra

    • Rochester Institute of Technology

  • Wallace F Marshall

    • UC San Francisco
    • UCSF
    • University of California, San Francisco

  • Sindy K Tang,

    • Stanford University

  • Moumita Das

    • Rochester Institute of Technology

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• The cellular biomechanics of wound resistance in the giant ciliate protozoa Stentor coeruleus

  ORAL

  March 17, 2025, 12:42 PM – March 17, 2025, 12:54 PM

  Presenters

  • Rajorshi Paul

    • Stanford University

  Authors

  • Rajorshi Paul

    • Stanford University

  • Justine E Sato

    • Stanford University

  • Ambika V Nadkarni

    • Stanford University

  • Kevin S Zhang

    • Stanford University

  • Moumita Das

    • Rochester Institute of Technology

  • Wallace F Marshall

    • UC San Francisco
    • UCSF
    • University of California, San Francisco

  • Sindy K Tang,

    • Stanford University

  View abstract →

• Mechanical waves identify the amputation position during wound healing in the amputated zebrafish tailfin

  ORAL

  March 17, 2025, 12:54 PM – March 17, 2025, 1:06 PM

  Publication: Nature Physics 19, 1362-1370 (2023)

  Presenters

  • Keng-hui Lin

    • Institute of Physics, Academia Sinica

  Authors

  • Keng-hui Lin

    • Institute of Physics, Academia Sinica

  • Fu-lai Wen

    • Department of Physics, National Central University

  • Chen-hui Chen

    • Institute of Cellular and Organismic Biology, Academia Sinica

  • Marco De Leon

    • Cardiovascular Research Institute, University of California, San Francisco

  View abstract →

• Vertex Model of Wound Healing Mechanics in Drosophila Epithelia

  ORAL

  March 17, 2025, 1:06 PM – March 17, 2025, 1:18 PM

  Publication: I. Han et al, Molecular Biology of the Cell, May 2024

  Presenters

  • Kaden J Tro

    • Vanderbilt University

  Authors

  • Kaden J Tro

    • Vanderbilt University

  • Ivy Han

    • Vanderbilt University

  • Shane Hutson

    • Vanderbilt University

  • Andrea Page-McCaw

    • Vanderbilt University

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• Stability of Cell-Cell Junctions: Balancing Cortical Tension and Cadherin Aggregation at cell interface during cell-cell separation.

  ORAL

  March 17, 2025, 1:18 PM – March 17, 2025, 1:30 PM

  Presenters

  • Suraj Kumar Sahu

    • University of California, Merced

  Authors

  • Suraj Kumar Sahu

    • University of California, Merced

  • Ajay Gopinathan

    • University of California, Merced
    • Dept. of Physics, UC Merced
    • Department of Physics, University of California, Merced

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• Effects of dissipative junctional adhesion on confluent tissue viscoelasticity and dynamics

  ORAL

  March 17, 2025, 1:30 PM – March 17, 2025, 1:42 PM

  Presenters

  • Anh Quoc Nguyen

    • Northeastern University

  Authors

  • Anh Quoc Nguyen

    • Northeastern University

  • Dapeng Bi

    • Northeastern Univeristy

  • Praveen Kumar

    • Northeastern University

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• Simulations of fluid flow in multicellular systems

  ORAL

  March 17, 2025, 1:42 PM – March 17, 2025, 1:54 PM

  Presenters

  • John D Treado

    • Cluster of Excellence Physics of Life, TU Dresden

  Authors

  • John D Treado

    • Cluster of Excellence Physics of Life, TU Dresden

  • Otger Campas

    • Cluster of Excellence Physics of Life, TU Dresden

  • Frank Jülicher

    • Max Planck Institute for the Physics of Complex Systems

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• Cell size heterogeneity controls crystallization of the developing fruit fly wing

  ORAL

  March 17, 2025, 1:54 PM – March 17, 2025, 2:06 PM

  Presenters

  • Kartik Chhajed

    • Max Planck Institute for Physics of Complex Systems

  Authors

  • Kartik Chhajed

    • Max Planck Institute for Physics of Complex Systems

  • Natalie Dye

    • Cluster of Excellence Physics of Life, Technical University Dresden

  • Frank Jülicher

    • Max Planck Institute for the Physics of Complex Systems

  • Marko Popovic

    • Max Planck Institute for Physics of Complex Systems

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• Dynamic Shape Adaptation: Understanding the Relationship Between Cell Shape and Motion inCell Monolayers

  ORAL

  March 17, 2025, 2:06 PM – March 17, 2025, 2:18 PM

  Presenters

  • Gautham Gopinath

    • Yale University

  Authors

  • Gautham Gopinath

    • Yale University

  • Emmanuel Y Mintah

    • Yale University

  • Mark D Shattuck

    • The City College of New York

  • Corey S O'Hern

    • Yale University

  View abstract →