Liquid Crystals in Biology: Form, Functions and Applications

Presentations

• Patterned liquid crystal elastomers to control layers of normal and cancer cells

  ORAL · Invited

  March 18, 2025, 3:00 PM – March 18, 2025, 3:36 PM

  Publication: T. Turiv, J. Krieger, G. Babakhanova, H. Yu, S. V. Shiyanovskii, Q.-H. Wei, M.-H. Kim, O. D. Lavrentovich, Topology control of human fibroblast cells monolayer by liquid crystal elastomer. Sci. Adv. 6, eaaz6485 (2020).

  Presenters

  • Oleg D Lavrentovich

    • Kent State University

  Authors

  • Oleg D Lavrentovich

    • Kent State University

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• Formation of 3D cell mounds at topological defects

  ORAL · Invited

  March 18, 2025, 3:36 PM – March 18, 2025, 4:12 PM

  Publication: - Sarkar T et al. Crisscross multilayering of cell sheets. PNAS Nexus (2023); 2(3): 1–27.
  - Lacroix M et al. in preparation
  - Chen HY et al. in preparation.

  Presenters

  • Pascal Silberzan

    • Institut Curie, Paris

  Authors

  • Pascal Silberzan

    • Institut Curie, Paris

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• 3D nematic organization and topological defects in brain tumors in vivo.

  ORAL

  March 18, 2025, 4:12 PM – March 18, 2025, 4:24 PM

  Publication: Comba, A., Faisal, S.M., Dunn, P.J.,..., and Lowenstein, P.R.. Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression. Nature Communications 13, 3606 (2022). https://doi.org/10.1038/s41467-022-31340-1
  Faisal, Syed M.,..., and Lowenstein, P.R. "Spatiotemporal Insights into Glioma Oncostream Dynamics: Unraveling Formation, Stability, and Disassembly Pathways." Advanced Science; vol. 11,18 (2024): e2309796. doi:10.1002/advs.202309796
  Argento, A.E., Varela, M. L., Edwards, M.B., Beller, D., Castro, M. G., Blanch-Mercader, C.& Lowenstein, P. R. "Brain tumors are ordered as active liquid crystals." 2024. To Be Submitted.
  

  Presenters

  • Pedro R Lowenstein

    • University of Michigan

  Authors

  • Pedro R Lowenstein

    • University of Michigan

  • Anna E Argento

    • University of Michigan

  • Binyamin Jacoobovitz

    • University of Michigan

  • Daniel A Beller

    • Johns Hopkins University

  • Maria G Castro

    • University of Michigan

  • Carles Blanch-Mercader

    • Institut Curie

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• Density-driven alignment and defect annihilation in cell monolayers

  ORAL

  March 18, 2025, 4:24 PM – March 18, 2025, 4:36 PM

  Presenters

  • Yimin Luo

    • Yale University

  Authors

  • Yimin Luo

    • Yale University

  • Yuxin Luo

    • Yale University

  • Shervin Issakhani

    • Yale University

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• Hierarchical Tissue-like Material from Nematic Synthetic Colloids with Adaptive Internal Microstucture

  ORAL

  March 18, 2025, 4:36 PM – March 18, 2025, 4:48 PM

  Presenters

  • Chuqiao Chen

    • University of Chicago

  Authors

  • Chuqiao Chen

    • University of Chicago

  • Viviana Palacio-Betancur

    • University of Chicago

  • Nina Chang

    • University of Chicago

  • Kaitlin Landy

    • University of Chicago

  • Annie Zhi

    • University of Chicago

  • Stuart J Rowan

    • UChicago

  • Juan J De Pablo

    • University of Chicago

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• Molecular Dynamics Simulation of Thin Rods with an Analytical Interaction Potential

  ORAL

  March 18, 2025, 4:48 PM – March 18, 2025, 5:00 PM

  Publication: J. Wang, G. D. Seidel, S. Cheng, arXiv:2405.03941

  Presenters

  • Junwen Wang

    • Virginia Tech

  Authors

  • Junwen Wang

    • Virginia Tech

  • Gary D Seidel

    • Virginia Tech

  • Shengfeng Cheng

    • Virginia Tech

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• Boundary-Guided Topological Entropy Production in Confined Active Nematics

  ORAL

  March 18, 2025, 5:00 PM – March 18, 2025, 5:12 PM

  Presenters

  • Brandon Klein

    • Johns Hopkins University

  Authors

  • Brandon Klein

    • Johns Hopkins University

  • Alejandro Soto Franco

    • Johns Hopkins University

  • Md Mainul Hasan Sabbir

    • University of California, Merced

  • Kevin A Mitchell

    • University of California, Merced

  • Daniel A Beller

    • Johns Hopkins University

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• Influence of flow structures on defect dynamics in 3D active nematics

  ORAL

  March 18, 2025, 5:12 PM – March 18, 2025, 5:24 PM

  Publication: Head, L.C. et al. Spontaneous self-constraint in active nematic flows. Nat. Phys. 20, 492–500 (2024).

  Presenters

  • Louise C Head

    • Johns Hopkins University

  Authors

  • Louise C Head

    • Johns Hopkins University

  • Giuseppe Negro

    • University of Edinburgh

  • Tyler N Shendruk

    • Univ of Edinburgh

  • Daniel A Beller

    • Johns Hopkins University

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• Abstract Withdrawn

  ORAL · Withdrawn

  March 18, 2025, 5:24 PM – March 18, 2025, 5:36 PM

  View abstract →

• Characterization of Dynamically Restructuring Soft Materials with High Throughput Microscopy Techniques

  ORAL

  March 18, 2025, 5:36 PM – March 18, 2025, 5:48 PM

  Presenters

  • Aditya Sriram

    • University of San Diego

  Authors

  • Aditya Sriram

    • University of San Diego

  • Qiaopeng Chen

    • University of California, Santa Barbara

  • Ayan Das

    • University of California, Santa Barbara

  • Katarina Matic

    • University of San Diego

  • Jonathan A Michel

    • Rochester Institute of Technology

  • Maya Hendija

    • University of San Diego

  • Nimisha Krishnan

    • Syracuse University

  • Keegan S Tonry

    • Rochester Institute of Technology

  • Michael J Rust

    • University of Chicago

  • Jennifer L Ross

    • Syracuse University

  • Moumita Das

    • Rochester Institute of Technology

  • Ryan J. McGorty

    • University of San Diego

  • Megan T Valentine

    • University of California, Santa Barbara

  • Rae M Robertson-Anderson

    • University of San Diego

  View abstract →