Force Velocity for Contracting Actomyosin Networks
ORAL
Abstract
Reconstituted actomyosin protein networks exhibit contractile dynamics like many living systems, with far less complexity. Previous studies have characterized molecular motors through single molecule force-velocity measurements. We experimentally quantify the forces generated in contractile actomyosin networks. To measure the force-velocity relationship of the actomyosin contractile network we embed an extensile spring-like network that opposes actomyosin contractions. By varying both extensile resistance and protein concentrations we explore actomyosin contractile dynamics for a range of experimental conditions.
*We would like to acknowledge and thank the Worster Family for their support of this project.
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Presenters
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Jasper Reid
- University of California, Santa Barbrara