Quantitative Cell Physiology II

Presentations

• Abstract Withdrawn

  ORAL · Withdrawn

  March 21, 2025, 8:00 AM – March 21, 2025, 8:12 AM

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• How does homeostasis emerge from the activities of many individual enzymes?

  ORAL

  March 21, 2025, 8:12 AM – March 21, 2025, 8:24 AM

  Publication: https://www.biorxiv.org/content/10.1101/2022.12.28.522046

  Presenters

  • Denis Titov

    • University of California, Berkeley

  Authors

  • Denis Titov

    • University of California, Berkeley

  • Tal Einav

    • Caltech

  • Rob Phillips

    • Caltech

  • Mangyu Choe

    • UT Southwestern

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• Protein titration as the driver of precision control in bacteria

  ORAL

  March 21, 2025, 8:24 AM – March 21, 2025, 8:36 AM

  Presenters

  • Haochen Fu

    • University of California, San Diego

  Authors

  • Haochen Fu

    • University of California, San Diego

  • Dongyang Li

    • California Institute of Technology
    • University of California, San Diego

  • Suckjoon Jun

    • University of California, San Diego

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• Protein overabundance is driven by growth robustness

  ORAL

  March 21, 2025, 8:36 AM – March 21, 2025, 8:48 AM

  Publication: Lo TW, Choi HJ, Huang D, Wiggins PA (2024) Noise robustness and metabolic load determine the principles of central dogma regulation. Science Advances 10(34)
  
  Choi HJ, Lo TW, Cutler KJ, Huang D, Will WR, Wiggins PA (2024) Protein overabundance is driven by growth robustness. (Submitted to PNAS)

  Presenters

  • James Choi

    • University of Washington

  Authors

  • James Choi

    • University of Washington

  • Teresa W Lo

    • University of Washington

  • Ryan Will

    • University of Washington

  • Kevin Cutler

    • University of Washington

  • Dean Huang

    • University of Washington

  • Paul Wiggins

    • University of Washington

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• Evolutionary Origins of Cellular Adaptation and Stress Response Prioritization Revealed by Single-Cell Transcriptomics

  ORAL

  March 21, 2025, 8:48 AM – March 21, 2025, 9:00 AM

  Publication: In Prep: Evolutionary Origins of Cellular Adaptation and Stress Response Prioritization

  Presenters

  • Annisa Dea

    • University of Chicago

  Authors

  • Annisa Dea

    • University of Chicago

  • Yongqing Lan

    • University of Chicago

  • Valeryia Aksianiuk

    • University of Bern

  • Benjamin Doran

    • University of Chicago

  • Arjun Raman

    • University of Chicago

  • David Pincus

    • University of Chicago

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• Bifurcations and multistability in an inducible three-gene switch network

  ORAL

  March 21, 2025, 9:00 AM – March 21, 2025, 9:12 AM

  Presenters

  • Rebecca J Rousseau

    • Caltech

  Authors

  • Rebecca J Rousseau

    • Caltech

  • Rob Phillips

    • Caltech

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• Disentangling the cost of gene expression and the emerging central dogma regulation principles

  ORAL

  March 21, 2025, 9:12 AM – March 21, 2025, 9:24 AM

  Presenters

  • Yichen Yan

    • Peking University

  Authors

  • Yichen Yan

    • Peking University

  • Jie Lin

    • Peking University

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• Optimal control of cell proliferation at the molecular level

  ORAL

  March 21, 2025, 9:24 AM – March 21, 2025, 9:36 AM

  Presenters

  • R. Krishna Prahlaadh

    • University of Pittsburgh

  Authors

  • R. Krishna Prahlaadh

    • University of Pittsburgh

  • Motasem ElGamel

    • University of Pittsburgh

  • Farshid Jafarpour

    • University of Utrecht
    • Utrecht University

  • Andrew Mugler

    • University of Pittsburgh

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• Homeostasis of cytoplasmic crowding by cell wall fluidization and ribosomal counterions

  ORAL

  March 21, 2025, 9:36 AM – March 21, 2025, 9:48 AM

  Presenters

  • Markus Basan

    • Harvard University

  Authors

  • Markus Basan

    • Harvard University

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• Mitochondrial networks changes over the yeast cell-cycle:The topology, shape and size of mitochondrial networks during the cell cycle in yeast

  ORAL

  March 21, 2025, 9:48 AM – March 21, 2025, 10:00 AM

  Presenters

  • Aman Sharma

    • UCSD

  Authors

  • Aman Sharma

    • UCSD

  • Saransh Umale

    • UCSD

  • Suckjoon Jun

    • University of California, San Diego

  • Laura L Lackner

    • Northwestern University

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• A general mechanism for cell size control in yeast

  ORAL

  March 21, 2025, 10:00 AM – March 21, 2025, 10:12 AM

  Presenters

  • Lucas Ribaudo

    • University of Pittsburgh

  Authors

  • Lucas Ribaudo

    • University of Pittsburgh

  • Motasem ElGamel

    • University of Pittsburgh

  • Andrew Mugler

    • University of Pittsburgh

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• Mutation–induced stress accelerates bacterial aging and alters the senescence phenotype

  ORAL

  March 21, 2025, 10:12 AM – March 21, 2025, 10:24 AM

  Publication: Maryam Kohram, Amy Sanderson, Peyton V. Thompson, Alicia Loui, Harsh Vashistha, Aseel Shomar, Zoltán N. Oltvai, and Hanna Salman "Non-lethal deleterious mutation-induced stress accelerates bacterial aging". PNAS 121, e2316271121 (2024).

  Presenters

  • Hanna Salman

    • University of Pittsburgh

  Authors

  • Hanna Salman

    • University of Pittsburgh

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• Abstract Withdrawn

  ORAL · Withdrawn

  March 21, 2025, 10:24 AM – March 21, 2025, 10:36 AM

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• Coordination of nuclear and cellular volumes in fission yeast

  ORAL

  March 21, 2025, 10:36 AM – March 21, 2025, 10:48 AM

  Presenters

  • Joël Lemière

    • University of California, San Francisco

  Authors

  • Joël Lemière

    • University of California, San Francisco

  • Fred Chang

    • UCSF

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• Global stoichiometry conservation architecture of gene expression profiles revealed by cellular Raman spectra

  ORAL

  March 21, 2025, 10:48 AM – March 21, 2025, 11:00 AM

  Publication: Kamei, K.F., Kobayashi-Kirschvink, K.J., Nozoe, T., Nakaoka, H., Umetani, M. and Wakamoto, Y., 2023. Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns. bioRxiv.

  Presenters

  • Ken-ichiro F Kamei

    • The University of Tokyo

  Authors

  • Ken-ichiro F Kamei

    • The University of Tokyo

  • Koseki J Kobayashi-Kirschvink

    • Broad Institute of MIT and Harvard

  • Takashi Nozoe

    • The University of Tokyo

  • Hidenori Nakaoka

    • Tokushima University

  • Miki Umetani

    • The University of Tokyo

  • Yuichi Wakamoto

    • The University of Tokyo

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