DBIO Early Career Prize
FOCUS · MAR-A57 · ID: MAR-A57
Presentations
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Rapid evolution in complex microbial communities
Invited-In-person · Invited
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Presenters
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Benjamin Good
- Stanford University
Authors
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Benjamin Good
- Stanford University
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Cells navigate disordered networks through tension-guided pathways
Oral-In-person
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Presenters
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Sarthak Gupta
- Rice University
Authors
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Sarthak Gupta
- Rice University
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Shaoxun Huang
- Massachusetts Institute of Technology
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Haiqian Yang
- Massachusetts Institute of Technology
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Ming Guo
- Massachusetts Institute of Technology
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Fred MacKintosh
- RICE UNIVERSITY
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The actin filament pointed-end depolymerase Srv2/CAP depolymerizes barbed ends, displaces capping protein, and promotes formin processivity
Oral-In-person
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Publication: Reddy, V., Arya, A., & Shekhar, S. (2025). Twinfilin is a nonprocessive depolymerase which synergizes with formin to dramatically accelerate actin filament uncapping by 300-fold. Proceedings of the National Academy of Sciences, 122(18), e2501078122.
Nandi, M., Shekhar, S., & Choubey, S. (2025). A generalized theoretical framework to investigate multicomponent actin dynamics. PLOS Computational Biology, 21(9), e1013434.
Nguyen, P. D. N., Abe, H., Ono, S., & Kodera, N. (2025). Actin monomers influence the interaction between Xenopus cyclase-associated protein 1 and actin filaments. bioRxiv, 2025-08.
Actin Filament Barbed End Synergistic De-polymerization via C-CAP1 (preprint)Presenters
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Ekramuddin Towsif
- Emory University
Authors
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Ekramuddin Towsif
- Emory University
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Shashank Shekhar
- Emory university
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Non-monotonic energy dissipation under active stress in cytoskeletal networks
Oral-In-person
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Presenters
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Zachary Gao Sun
- Institute of Science and Technology Austria (ISTA)
Authors
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Zachary Gao Sun
- Institute of Science and Technology Austria (ISTA)
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Michael Murrell
- Yale University
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Joost Vlassak
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Juanjuan Zheng
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Torsional Mechanics of Circular DNA
Oral-In-person
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Publication: Torsional Mechanics of Circular DNA
Gundeep Singh, Yifeng Hong, James T. Inman, James P. Sethna, Michelle D. Wang
bioRxiv 2024.10.08.617281; doi: https://doi.org/10.1101/2024.10.08.617281Presenters
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Gundeep Singh
- Cornell University
Authors
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Gundeep Singh
- Cornell University
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Yifeng Hong
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James Inman
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James Sethna
- Cornell University
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Michelle Wang
- Cornell University
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Learning and Chattering: Bioelectric voltage spikes in epithelial cell monolayers
Oral-In-person
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Publication: 1. S. Yu, & S. Granick, Electric spiking activity in epithelial cells, Proc. Natl. Acad. Sci. U.S.A. 122 (12) e2427123122, https://doi.org/10.1073/pnas.2427123122 (2025).
Presenters
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Sun-Min Yu
- University of Massachusetts Amherst
Authors
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Sun-Min Yu
- University of Massachusetts Amherst
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Steve Granick
- University of Massachusetts Amherst
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DBIO Dissertation Award: Low-dimensional models of immune sensing and signaling
Invited-In-person · Invited
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Publication: Achar, Bourassa, Rademaker et al., "Universal antigen encoding of T cell activation from high-dimensional cytokine dynamics", Science, May 2022.
Gaud, Achar, Bourassa, Davies et al., "CD3zeta ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides", Nature Immunology, December 2023
Kondo, Bourassa, Achar et al., "Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity", Cell, May 2025.
Bourassa, "Low-dimensional models of immune sensing and signaling" [doctoral thesis], June 2024.Presenters
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François Bourassa
- Princeton University
Authors
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François Bourassa
- Princeton University
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Sooraj Achar
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Taisuke Kondo
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Thomas Rademaker
- McGill Univ
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Naomi Taylor
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Gregoire Altan-Bonnet
- NIH
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Paul Francois
- Universite de Montreal
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Design principles of the cytotoxic CD8<sup>+</sup> T-cell response
Oral-In-person
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Publication: O. Ukogu, Z. Montague, G. Altan-Bonnet, A. Nourmohammad, "Design principles of the cytotoxic CD8+ T-cell response," arXiv [physics.bio-ph] (2025). http://arxiv.org/abs/2509.22997.
Presenters
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Obinna Ukogu
- University of Washington
Authors
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Obinna Ukogu
- University of Washington
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Zachary Montague
- University of Washington
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Gregoire Altan-Bonnet
- NIH
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Armita Nourmohammad
- University of Washington
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Nonequilibrium phase separation couples growth to chromosome segregation in Escherichia coli
Oral-In-person
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Presenters
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Qiwei Yu
- Princeton University
Authors
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Qiwei Yu
- Princeton University
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Alexandros Papagiannakis
- Stanford University
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Sander Govers
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Wei-Hsiang Lin
- Academia Sinica
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Christine Jacobs-Wagner
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Ned Wingreen
- Princeton University
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Proposing patient-specific diabetes treatments using a mathematical theory of disease progression
Oral-In-person
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Publication: Sean A Ridout Priyathama Vellanki Ilya Nemenman (2025) A mathematical model for ketosis-prone diabetes suggests the existence of multiple pancreatic β-cell inactivation mechanisms
eLife 13:RP100193.
Manuscript on clinical results in preparation, not yet submitted.Presenters
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Sean Ridout
- Emory University
Authors
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Sean Ridout
- Emory University
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Priyathama Vellanki
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Ilya Nemenman
- Emory University
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Quantifying the compressibility of the human brain
Oral-In-person
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Publication: Weaver, N.J., Faskowitz, J.I., Betzel, R.F., Lynn. C.W. Quantifying the compressibility of the human brain. (2025). https://arxiv.org/abs/2510.16327
Presenters
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Nicholas Weaver
- Yale University
Authors
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Nicholas Weaver
- Yale University
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Joshua Faskowitz
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Richard Betzel
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Christopher Lynn
- Yale University
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