Physics of Cell Fate Transition I

Presentations

• Aging reduces robustness in regulating muscle stem cell fate decision and transition

  ORAL · Invited

  March 17, 2026, 8:00 AM – March 17, 2026, 8:36 AM

  Presenters

  • Amitava Giri

    • University of Pittsburgh

  Authors

  • Amitava Giri

    • University of Pittsburgh

  • Sophia Hu

    • University of Pittsburgh

  • Fabrisia Ambrosio

    • Harvard University

  • Thomas A Rando

    • University of California, Los Angeles

  • Jianhua Xing

    • University of Pittsburgh

  View abstract →

• Collective homeostasis in mean-field interacting systems

  ORAL

  March 17, 2026, 8:36 AM – March 17, 2026, 8:48 AM

  Presenters

  • Emmy Blumenthal

    • Princeton University

  Authors

  • Emmy Blumenthal

    • Princeton University

  • Gautam Reddy

    • Princeton University

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• Extending Boolean Models to Capture Hybrid Epithelial–Mesenchymal Phenotypes

  ORAL

  March 17, 2026, 8:48 AM – March 17, 2026, 9:00 AM

  Publication: A multilevel formalism to model the hybrid E/M phenotypes in Epithelial-Mesenchymal Plasticity
  Kishore Hari, Shubham Tripathi, Vaibhav Anand, Mohit Kumar Jolly, Herbert Levine
  bioRxiv 2024.11.26.625479; doi: https://doi.org/10.1101/2024.11.26.625479

  Presenters

  • Anantha Samrajya Shri Kishore Hari

    • Northeastern University

  Authors

  • Anantha Samrajya Shri Kishore Hari

    • Northeastern University

  • Herbert Levine

    • Northeastern University
    • Center for Theoretical Biological Physics, Northeastern University

  • Shubham Tripathi

    • Yale University

  • Mohit Kumar Jolly

    • Indian Institute of Science
    • Indian Institute of Science Bengaluru

  • Vaibhav Anand

    • Northeastern University

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• Co-fluctuations of genes in unperturbed single cells predict transcriptome-wide outcomes to genetic perturbations

  ORAL

  March 17, 2026, 9:00 AM – March 17, 2026, 9:12 AM

  Publication: biorxiv doi: https://doi.org/10.1101/2025.06.27.661814

  Presenters

  • Benjamin Kuznets-Speck

    • Northwestern University

  Authors

  • Benjamin Kuznets-Speck

    • Northwestern University

  • Yogesh Goyal

    • Northwestern University

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• Modeling subtype dynamics and heterogeneity in small cell lung cancer using ordinary differential equations

  ORAL

  March 17, 2026, 9:12 AM – March 17, 2026, 9:24 AM

  Presenters

  • Ziyi Liu

    • University of Texas at Dallas

  Authors

  • Ziyi Liu

    • University of Texas at Dallas

  • Tian Hong

    • University of Texas at Dallas

  • Darren Tyson

    • Duke University

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• Performing nonlinear stability analysis for a highly interconnected gene network model

  ORAL

  March 17, 2026, 9:24 AM – March 17, 2026, 9:36 AM

  Presenters

  • Nimasha Samarawickrama

    • University of North Dakota

  Authors

  • Nimasha Samarawickrama

    • University of North Dakota

  • Yen Lee Loh

    • University of North Dakota

  • Manu Manu

    • University of North Dakota

  • Andrea Repele

    • University of North Dakota

  • Joanna Handzlik

    • University of North Dakota

  • Nimasha Samarawickrama

    • University of North Dakota

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• Leveraging Twin Information for Inference of Gene Regulatory Networks

  ORAL

  March 17, 2026, 9:36 AM – March 17, 2026, 9:48 AM

  Presenters

  • Yuval Scher

    • Northwestern University

  Authors

  • Yuval Scher

    • Northwestern University

  • Keerthana M Arun

    • Northwestern University

  • Yuhan Zhang

    • Northwestern University

  • Benjamin Kuznets-Speck

    • Northwestern University

  • Ida Büschel

    • Helmholtz Munich

  • Carsten Marr

    • Helmholtz Munich

  • Yogesh Goyal

    • Northwestern University

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• Classifying cell fate transitions in high-dimensional gene regulatory networks

  ORAL

  March 17, 2026, 9:48 AM – March 17, 2026, 10:00 AM

  Publication: Finding signatures of low-dimensional geometric landscapes in
  high-dimensional cell fate transitions
  scTOP: physics-inspired order parameters for cellular identification and visualization

  Presenters

  • Maria Yampolskaya

    • Université de Montréal

  Authors

  • Maria Yampolskaya

    • Université de Montréal

  • Paul Francois

    • Université de Montréal

  • Pankaj Mehta

    • Boston University

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• The Cost of Biological Rhythms: From Dynamical Systems to Thermodynamics

  ORAL

  March 17, 2026, 10:00 AM – March 17, 2026, 10:12 AM

  Publication: arxiv2507.20750

  Presenters

  • YeongKyu Lee

    • Korea Institute for Advanced Study

  Authors

  • YeongKyu Lee

    • Korea Institute for Advanced Study

  • Changbong Hyeon

    • Korea Institute for Advanced Study

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• High-Throughput Mechanomic Screening Reveals Novel Regulators of Single-Cell Mechanics

  ORAL

  March 17, 2026, 10:12 AM – March 17, 2026, 10:24 AM

  Publication: Strampe L, Plak K, Schweitzer C, Liebers C, Müller P, Urbanska M, Kräter
  M, Baum B, Kayser J, Guck J, High-Throughput Mechanomic Screening Reveals Novel Regulators of
  Single-Cell Mechanics, Biophysical Journal (2025), doi: https://doi.org/10.1016/j.bpj.2025.10.008

  Presenters

  • Laura von Selzam

    • Max Planck Institute for the Science of Light

  Authors

  • Laura von Selzam

    • Max Planck Institute for the Science of Light

  • Katarzyna Plak

    • Technische Universität Dresden

  • Christine Schweitzer

    • Max Planck Institute for the Science of Light

  • Cornelia Liebers

    • Max Planck Institute for the Science of Light

  • Paul Müller

    • Max Planck Institute for the Science of Light

  • Marta Urbanksa

    • University of Cambridge

  • Martin Kräter

    • Max Planck Institute for the Science of Light

  • Buzz Baum

    • Medical Research Council Laboratory of Molecular Biology

  • Jona Kayser

    • Max Planck Institute for the Science of Light

  • Jochen Guck

    • Max Planck Institute for the Science of Light

  View abstract →