Physical Mechanisms of Chromatin Regulation of Genome Accessibility

Presentations

• Single-molecule force-fluorescence studies of genetic and epigenetic machinery

  ORAL · Invited

  March 18, 2026, 3:30 PM – March 18, 2026, 4:06 PM

  Presenters

  • Shixin Liu

    • Rockefeller University

  Authors

  • Shixin Liu

    • Rockefeller University

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• Nucleosome flipping drives selectivity and processivity of histone exchange by SWR1

  ORAL · Invited

  March 18, 2026, 4:06 PM – March 18, 2026, 4:42 PM

  Presenters

  • Paul Girvan

  Authors

  • Paul Girvan

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• Quantitative imaging of nanoscale chromatin architecture in the nucleus of a living cell

  ORAL · Invited

  March 18, 2026, 4:42 PM – March 18, 2026, 5:18 PM

  Presenters

  • Elizabeth Hinde

    • University of Melbourne

  Authors

  • Elizabeth Hinde

    • University of Melbourne

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• Choreography of chromatin regulation captured on the molecular level

  ORAL · Invited

  March 18, 2026, 5:18 PM – March 18, 2026, 5:54 PM

  Publication: [1] Teslenko A, Fierz B. Single-molecule analysis reveals the mechanism of chromatin ubiquitylation by variant PRC1 complexes. Sci Adv. 2025 May 23;11(21):eadt7013
  [2] Sakong, S., Fierz., B., Suter, D., Electrostatic properties of disordered regions control transcription factor search and pioneer activity,
  bioRxiv 2025.03.07.641980; doi: https://doi.org/10.1101/2025.03.07.641980

  Presenters

  • Beat Fierz

    • EPFL

  Authors

  • Beat Fierz

    • EPFL

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• Chromatin Distortions as drivers of Genome Function and Dysfunction

  ORAL · Invited

  March 18, 2026, 5:54 PM – March 18, 2026, 6:30 PM

  Publication: https://elifesciences.org/articles/86709

  Presenters

  • Yamini Dalal

    • NIH

  Authors

  • Yamini Dalal

    • NIH

  View abstract →