Virtual Mode Sorting: A Hardware-Free Path to Super-Resolution Imaging Across Wavelengths

ORAL

Abstract

The diffraction limit is often treated as a hard barrier in imaging, but in reality a surprising amount of high-frequency information is still present in a blurred image, it’s just not directly accessible. Many groups have tried to recover this hidden structure using specialized optics or interferometry, but these approaches require careful alignment and are not practical outside controlled lab settings. In this work, we show that it is possible to go beyond the diffraction limit using only standard intensity images from an ordinary camera. Our method, which we call virtual mode sorting, analyzes images by projecting them onto a set of spatial modes that preserve fine structure normally lost to blur. This allows us to recover sub-diffraction information in a stable and physically meaningful way, without deconvolution or learned priors. We demonstrate a significant resolution improvement in both optical and acoustic imaging experiments, showing that the approach is wavelength-independent and works for incoherent systems as well. The method has a built-in parameter that lets the user balance resolution gain against noise sensitivity, and it remains robust in low signal-to-noise conditions, especially when paired with simple denoising. The key advantage is practicality: there is no need for calibrated hardware, wavefront control, or interferometry. Virtual mode sorting can be used as a drop-in upgrade for existing microscopes, ultrasound systems, or remote imaging platforms, making super-resolution achievable in real-world settings rather than just idealized experiments.

*M.H. and L.C. acknowledges support from the National Science Foundation (CAREER Award No. 2239004) and the Catalysing Research Teaming (CRT) award from the College of Engineering and Applied Science at the University of Colorado Boulder. This work utilized research computing resources at the University of Colorado Boulder Research Computing, which is supported by NSF (ACI-1532235 and ACI-1532236), University of Colorado Boulder, and Colorado State University. We also acknowledge the support of the NSF ASCEND Engine in Colorado and Wyoming for providing computing resources at UW Advanced Research Computing Center (ARCC).

Publication: M. Habibi, Y. Zhu, D. Chooi, R. Piestun, Y. Chen, N. Bienert, N. Bottenus, T. Murray, and L. Cui. Wavelength and domain-agnostic superresolution imaging enabled by virtual mode sorting. Submitted to Nature

Presenters

  • Mohammad Habibi

    • University of Colorado Boulder

Authors

  • Mohammad Habibi

    • University of Colorado Boulder
  • Yunxuan Zhu

    • University of Colorado Boulder
  • Di Shan Chooi

    • University of Colorado Boulder
  • Rafael Piestun

    • University of Colorado Boulder
  • Yu Chih Chen

    • University of Pittsburgh
  • Nicole Bienert

    • University of Colorado Boulder
  • Nick Bottenus

    • University of Colorado Boulder
  • Todd Murray

    • University of Colorado, Boulder
  • Longji Cui

    • University of Colorado Boulder