Macromolecular Organization in Cells

Presentations

• Phase separated VASP droplets modulate actin filament assembly and dynamics

  ORAL

  March 20, 2026, 8:00 AM – March 20, 2026, 8:12 AM

  Presenters

  • Seongsoo Kim

    • The University of Chicago

  Authors

  • Seongsoo Kim

    • The University of Chicago

  • Kaitlin Landy

    • The University of Chicago

  • Della Waldman

    • The University of Chicago

  • David R Kovar

    • The University of Chicago

  • Margaret L Gardel

    • University of Chicago

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• Identifying molecular factors of polymorphic bacterial microcompartment assembly through coarse-grained simulations

  ORAL

  March 20, 2026, 8:12 AM – March 20, 2026, 8:24 AM

  Presenters

  • Emiel Kram

    • Colorado School of Mines

  Authors

  • Emiel Kram

    • Colorado School of Mines

  • Alexander J Pak

    • Colorado School of Mines

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• Bringing whole-cell models to life: Development of physics-based AI for accelerated modeling

  ORAL

  March 20, 2026, 8:24 AM – March 20, 2026, 8:36 AM

  Presenters

  • Roseanna N Zia

    • University of Missouri

  Authors

  • Roseanna N Zia

    • University of Missouri

  • Vishal Sankar Sivasankar

    • University of Missouri

  • Harnoor Singh Sachar

    • University of Missouri-Columbia
    • University of Texas at Austin

  • J. Galen Wang

    • Lawrence Berkeley National Laboratory

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• Multi-omics-based sequence-structure-function prediction

  ORAL · Invited

  March 20, 2026, 8:36 AM – March 20, 2026, 9:12 AM

  Publication: https://doi.org/10.1103/l2dp-kw2t
  https://doi.org/10.1021/acs.jcim.5c01661
  https://arxiv.org/abs/2507.21336

  Presenters

  • Margaret S Cheung

    • Pacific Northwest National Laboratory (PNNL)
    • Pnnl

  Authors

  • Margaret S Cheung

    • Pacific Northwest National Laboratory (PNNL)
    • Pnnl

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• Decision making through self-assembly on membranes

  ORAL

  March 20, 2026, 9:12 AM – March 20, 2026, 9:24 AM

  Publication: https://arxiv.org/abs/2505.17290

  Presenters

  • Margaret E Johnson

    • Johns Hopkins University

  Authors

  • Margaret E Johnson

    • Johns Hopkins University

  • Samuel Lincoln Foley

    • Johns Hopkins University

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• Molecular sorting on a fluctuating membrane

  ORAL

  March 20, 2026, 9:24 AM – March 20, 2026, 9:36 AM

  Publication: "Molecular sorting on a fluctuating membrane"
  Damiano Andreghetti, Luca Dall'Asta, Andrea Gamba, Igor Kolokolov, Vladimir Lebedev
  SciPost Phys. 18, 099 (2025) · published 18 March 2025
  10.21468/SciPostPhys.18.3.099

  Presenters

  • Damiano Andreghetti

    • Polytechnic University of Turin

  Authors

  • Damiano Andreghetti

    • Polytechnic University of Turin

  • Luca Dall'Asta

    • Polytechnic University of Turin

  • Andrea Gamba

    • Polytechnic University of Turin

  • Igor Kolokolov

    • L.D. Landau Institute for Theoretical Physics

  • Vladimir Lebedev

    • L.D. Landau Institute for Theoretical Physics

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• Inferring the Hierarchical Order in Macromolecular Spatial Organization Across Cell Phenotypes from Proteome Datasets Using a Grand Canonical Framework

  ORAL

  March 20, 2026, 9:36 AM – March 20, 2026, 9:48 AM

  Presenters

  • Jiayi Wang

    • University of Washington

  Authors

  • Jiayi Wang

    • University of Washington

  • Jules Nde

    • 2. Department of Cancer Biology, University of Kansas Medical Center

  • Andrei Gasic

    • R&D department, GOWell International LLC

  • Jacob Haseley

    • University of Washington

  • Margaret S Cheung

    • Pacific Northwest National Laboratory (PNNL)
    • Pnnl

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• Physically resolved Whole-Cell Colloidal Modeling of Escherichia coli Reveals Growth-Dependent Nucleoid Organization

  ORAL

  March 20, 2026, 9:48 AM – March 20, 2026, 10:00 AM

  Presenters

  • Vishal Sankar Sivasankar

    • University of Missouri

  Authors

  • Vishal Sankar Sivasankar

    • University of Missouri

  • Gesse Roure

    • University of Missouri

  • Roseanna N Zia

    • University of Missouri

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• Simulating large-scale dynamics in biomolecular assemblies

  ORAL

  March 20, 2026, 10:00 AM – March 20, 2026, 10:12 AM

  Presenters

  • Paul C Whitford

    • Northeastern University

  Authors

  • Paul C Whitford

    • Northeastern University

  • George Wanes

    • Northeastern University

  • Udayan Mohanty

    • Boston College

  • Raven Gallenstein

    • Boston College

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• Identifying Strain-Driven Mechanisms of Surface Layer Disassembly Through Multiscale Modeling

  ORAL

  March 20, 2026, 10:12 AM – March 20, 2026, 10:24 AM

  Presenters

  • Adam J Cecil

    • Colorado School of Mines

  Authors

  • Adam J Cecil

    • Colorado School of Mines

  • Alexander J Pak

    • Colorado School of Mines

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• Sloppy and stiff directions in parameter space and the fidelity of meiotic exit in budding yeast

  ORAL

  March 20, 2026, 10:24 AM – March 20, 2026, 10:36 AM

  Presenters

  • Viridiana Abigail Marquez Davila

    • Department of Physics, Indiana University Bloomington

  Authors

  • Viridiana Abigail Marquez Davila

    • Department of Physics, Indiana University Bloomington

  • Sima Setayeshgar

    • Department of Physics, Indiana University Bloomington

  • Soni Lacefield

    • Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth

  • Pallavi Gadgil

    • Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth

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• Flow-Driven Deformation and Transitions of Healthy and Diseased Red Blood Cells

  ORAL

  March 20, 2026, 10:36 AM – March 20, 2026, 10:48 AM

  Presenters

  • RAJ GAURAV

    • IIT MADRAS

  Authors

  • RAJ GAURAV

    • IIT MADRAS

  • Sainath Hareendranath

    • IIT MADRAS

  • Pallab Sinha Mahapatra

    • IIT MADRAS

  • SARITH P SATHIAN

    • IIT MADRAS
    • Indian Institute of Technology Madras

  View abstract →