HemaDropTM -- A New Technology To Perform Blood Analysis On Microliter\textunderscore Sized Droplets Of Blood By Creating Homogeneous Thin Solid Films (HTSF): Elemental Analysis Study As A Function Of Sampled Blood Volume

Currently, blood diagnostics requires 7~milliliters of blood, causing anemia in chronically ill or pediatric patients.~Decreasing that~volume by three orders of magnitude eliminates~that iatrogenic problem. HemaDrop\texttrademark [1]~congeals microliters-sized droplets of blood into Homogenous Thin Solid Films (HTSFs) as solid samples for analysis [2] via hyper-hydrophilic surfaces so droplets form a planar HTSF without phase segregation. ~HTSF's enables blood to be characterized by Ion Beam Analysis (IBA). The~damage curve method is used to account for ion beam damage.. After an initial study on canine blood [2], IBA is conducted on human blood. Blood diagnostics~need~reproducible, accurate results. To establish whether IBA ~meets this need on HemaDrop\texttrademark HTSF, IBA elemental concentration is measured as a function of HemaDrop\texttrademark droplets size. ~ [1] International {\&} US Patent~Herbots~\textit{et al}~(2016) [2] Pershad Y, Herbots N et al, MRS Advances (2016)