Nuclear Spin Diffusion Effects in Hyperpolarized [1-13C] Pyruvic Acid

ORAL

Abstract

Increasing the concentration of 13C nuclei in a sample is frequently used in dynamic nuclear polarization (DNP) to raise the resulting nuclear magnetic resonance (NMR) signal. However, the exact relation between polarization and concentration does not seem to be currently known. In order to make some progress in this area, this study looked at the effect of altering the 13C concentration upon the 13C hyperpolarization and spin-lattice relaxation time of [1-13C] pyruvic acid, doped with 15 mM trityl OX063, at 3.35 T and 1.2 K. It was determined that both the 13C polarization and the 13C spin-lattice relaxation time roughly obeyed an inverse exponential equation: both increased asymptotically for sufficiently low concentrations of 13C nuclei. These two observations were discussed in light of spin diffusion and dipole-dipole interactions.

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Presenters

  • Christopher Parish

    University of Texas at Dallas, the University of Texas at Dallas, University of Texas, Dallas

Authors

  • Christopher Parish

    University of Texas at Dallas, the University of Texas at Dallas, University of Texas, Dallas

  • Qing Wang

    University of Texas at Dallas, the University of Texas at Dallas, University of Texas, Dallas

  • Joseph Griesbauer

    University of Texas at Dallas, University of Dallas, University of Texas at Dallas

  • Fatemeh Khashami

    University of Texas at Dallas, the University of Texas at Dallas

  • Lloyd Lumata

    University of Texas, Dallas, University of Texas at Dallas