Visualization of DNA-Protein Complexes using Atomic Force Microscopy

ORAL

Abstract

Nowadays, it's been given increased attention to biological molecules, such as proteins in our bodies and DNA, because of their structural features, physical properties and interactions with other molecules, when viewed as nano-structures. In our research we focus our attention on DNA-Low Density Lipoprotein (LDL) interactions and different ways of visualizing these complexes and characterize their physical properties using Atomic Force Microscopy (AFM) as our main tool. The final purpose of this analysis is to identify specific interactions among LDL's and DNA that may help us unveil the possibility of using these LDL-DNA complexes as natural vectors for gene expression.

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Authors

  • Kevin Boos

    Angelo State University, Texas State University, San Marcos, SEMATECH, Texas State University, University of Texas at Brownsville, Abilene Christian University, Texas Tech University, University of Texas at Austin, Maypearl High School, Birdville ISD, South Texas Chapter, Health Physics Society, Sam Houston State University, NASA Johnson Space Center, Dept. of Physics, U. de Buenos Aires, Argentina, Dept.of Physics, ESFM-IPN, Mexico City, University of Texas M.D. Anderson Cancer Center, Rutgers University, Texas A\&M University, Istanbul University, University of North Texas, University of Texas at El Paso, Texas Christian University, Lee College, Southern University and A\&M College, Austin Community College, Rapoport Academy, Texas A\&M University, Kingsville, The University of Texas at Arlington, Tyler Junior College, Tarleton State University, Tolar High School, Granbury High School, Lake Highlands High School

  • Kevin Boos

    Angelo State University, Texas State University, San Marcos, SEMATECH, Texas State University, University of Texas at Brownsville, Abilene Christian University, Texas Tech University, University of Texas at Austin, Maypearl High School, Birdville ISD, South Texas Chapter, Health Physics Society, Sam Houston State University, NASA Johnson Space Center, Dept. of Physics, U. de Buenos Aires, Argentina, Dept.of Physics, ESFM-IPN, Mexico City, University of Texas M.D. Anderson Cancer Center, Rutgers University, Texas A\&M University, Istanbul University, University of North Texas, University of Texas at El Paso, Texas Christian University, Lee College, Southern University and A\&M College, Austin Community College, Rapoport Academy, Texas A\&M University, Kingsville, The University of Texas at Arlington, Tyler Junior College, Tarleton State University, Tolar High School, Granbury High School, Lake Highlands High School