Monte Carlo and numerical study of pumping $K_{\alpha}$ resonance fluorescence in high-Z nanovehicles for enhancing radiation therapy

POSTER

Abstract

Using the Monte Carlo code GEANT4 developed by CERN as well as a custom code called PHOTX, we have studied fluorescence and Auger electrons in a variety of nanoparticles as a method to improve tumor irradiation. We used GEANT4 to simulate photons from quasi-monochromatic, monochromatic, and traditional broadband medical X-ray sources interacting with heavy element nanoparticles designed to enhance X-ray absorption [1]. Nanoparticles were composed of gold, platinum, or gadolinium, were varied in size from 2-20 nm, and were varied in shape including rods, spheres, and cubes. We also have made developments to the code PHOTX to better implement Rabi floppings in order to determine intensities needed to pump $K_{\alpha}$ resonance fluorescence in high-Z nanovehicles [2].\newline [1] M. S. Westphal et al., Phys. Med. Biol, 62: 6361-6378, 2017.\newline [2] S. N. Nahar and A. K. Pradhan, JQSRT, 155: 32-48, 2015.

Authors

  • Maximillian Westphal

    Biophysics Graduate Program, The Ohio State University

  • Sultana Nahar

    Ohio State Univ - Columbus, Department of Astronomy, The Ohio State University, Te Ohio State University

  • Anil Pradhan

    Ohio State Univ - Columbus, Biophysics Graduate Program, Department of Astronomy, Chemical Physics Graduate Program, The Ohio State University, Te Ohio State University