Biomolecular Complexation and Liquid-Liquid Phase Separation

Presentations

• Transition of Polyelectrolyte Complexes from Solid-Liquid to Liquid-Liquid Systems through Enzymatic Degradation

  ORAL

  March 17, 2025, 3:00 PM – March 17, 2025, 3:12 PM

  Presenters

  • Whitney C Blocher McTigue

    • Lehigh University

  Authors

  • Whitney C Blocher McTigue

    • Lehigh University

  • Chaeyoung Lim

    • Lehigh University

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• Tunable Release of Encapsulated Proteins from Polyelectrolyte Complex Hydrogels

  ORAL

  March 17, 2025, 3:12 PM – March 17, 2025, 3:24 PM

  Presenters

  • Holly Senebandith

    • University of California, Los Angeles

  Authors

  • Holly Senebandith

    • University of California, Los Angeles

  • Khin C Pyone

    • University of California, Los Angeles

  • Maanasi D Narayan

    • University of California, Los Angeles

  • Marlo O Taylor

    • University of California, Los Angeles

  • Samanvaya Srivastava

    • University of California, Los Angeles
    • UCLA
    • UCLA Department of Chemical and Biomolecular Engineering

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• Charge Regulation in Intrinsically Disordered Proteins

  ORAL

  March 17, 2025, 3:24 PM – March 17, 2025, 3:36 PM

  Presenters

  • Souradeep Ghosh

    • Washington University in St. Louis
    • Washington University, St. Louis

  Authors

  • Souradeep Ghosh

    • Washington University in St. Louis
    • Washington University, St. Louis

  • Dylan T Tomares

    • Washington University, St. Louis

  • Daniel Palomo

    • Washington University, St. Louis

  • Rohit V Pappu

    • Washington University, St. Louis

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• Physics-driven coarse-grained models for understanding and engineering biomolecular condensates

  ORAL · Invited

  March 17, 2025, 3:36 PM – March 17, 2025, 4:12 PM

  Publication: Joseph JA†*, Reinhardt A†*, Aguirre A, Chew PY, Russell KO, Espinosa JR, Garaizar A, and Collepardo‑Guevara R*. Physics‑driven coarse‑grained model for biomolecular phase separation with near-quantitative accuracy. Nature Computational Science, 1, 732–743 (2021).
  
  Aierken D and Joseph JA*. Accelerated Simulations Reveal Physicochemical Factors Governing Stability and Composition of RNA Clusters. J. Chem. Theory Comput (2024).

  Presenters

  • Jerelle A Joseph

    • Princeton University
    • Chemical & Biological Engineering Princeton University, Omenn-Darling Bioengineering Institute
    • Princeton

  Authors

  • Jerelle A Joseph

    • Princeton University
    • Chemical & Biological Engineering Princeton University, Omenn-Darling Bioengineering Institute
    • Princeton

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• Utilization of Polyelectrolyte Complex (PEC) Microdroplets as Bioreactors

  ORAL

  March 17, 2025, 4:12 PM – March 17, 2025, 4:24 PM

  Presenters

  • Vihar Trada

    • University of Illinois Chicago
    • University of California, Los Angeles

  Authors

  • Vihar Trada

    • University of Illinois Chicago
    • University of California, Los Angeles

  • Advait Suhas Holkar

    • UCLA Department of Chemical and Biomolecular Engineering
    • University of California, Los Angeles

  • Samanvaya Srivastava

    • University of California, Los Angeles
    • UCLA
    • UCLA Department of Chemical and Biomolecular Engineering

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• Role of Surface Electrostatics in Particle-Polyelectrolyte Complex Coacervates

  ORAL

  March 17, 2025, 4:24 PM – March 17, 2025, 4:36 PM

  Presenters

  • Sirikarn Phuangthong

    • University of Illinois at Urbana-Champaign

  Authors

  • Sirikarn Phuangthong

    • University of Illinois at Urbana-Champaign

  • Ashley R Knoerdel

    • University of Illinois at Urbana-Champaign

  • Jason Madinya

    • University of Delaware

  • Charles E Sing

    • University of Illinois at Urbana-Champaign

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• Structure-property relationships for polyelectrolyte complexation with nucleic acids

  ORAL

  March 17, 2025, 4:36 PM – March 17, 2025, 4:48 PM

  Presenters

  • Alexander E Marras

    • University of Texas at Austin

  Authors

  • Alexander E Marras

    • University of Texas at Austin

  • Aasim F Hussain

    • University of Texas at Austin

  • Rakshit K Jain

    • University of Texas at Austin

  • Christian K Keys

    • University of Texas at Austin

  • John M Sansalone

    • University of Texas at Austin

  • Narayana R Aluru

    • The University of Texas at Austin
    • University of Texas at Austin

  • Thomas M Truskett

    • University of Texas at Austin

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• Uncovering the Critical Physiochemical Factors behind Polyelectrolyte Complexation with RNA

  ORAL

  March 17, 2025, 4:48 PM – March 17, 2025, 5:00 PM

  Publication: - Hussain AF*, Keys CK*, Houston JT, Marras AE. Impact of Nucleic Acid Structure and Sequence on Polyelectrolyte Complex Micelle Morphology. (manuscript in process)
  - Hussain AF, Sansalone JM, Chava BS, Keys CK, Arora AJ, Beshir NH, Aluru NR, Marras, AE. Polyelectrolyte complexation with RNA. (manuscript planned)

  Presenters

  • Aasim F Hussain

    • University of Texas at Austin

  Authors

  • Aasim F Hussain

    • University of Texas at Austin

  • John M Sansalone

    • University of Texas at Austin

  • Bhargav S Chava

    • University of Texas at Austin

  • Christian K Keys

    • University of Texas at Austin

  • Arora J Amrita

    • University of Texas at Austin

  • Nour H Beshir

    • University of Texas at Austin

  • Narayana R Aluru

    • The University of Texas at Austin
    • University of Texas at Austin

  • Alexander E Marras

    • University of Texas at Austin

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• Spectrophotometric Insights into Protein Encapsulation and Dilution in Polyelectrolyte Complex Micelles

  ORAL

  March 17, 2025, 5:00 PM – March 17, 2025, 5:12 PM

  Publication: Planned paper on Spectrophotometric Insights into Protein Encapsulation and Dilution in Polyelectrolyte Complex Micelles

  Presenters

  • Arthur Odenheimer

    • University of California, Los Angeles

  Authors

  • Arthur Odenheimer

    • University of California, Los Angeles

  • Holly Senebandith

    • University of California, Los Angeles

  • Justin R Caram

    • California State University, Los Angeles

  • Samanvaya Srivastava

    • University of California, Los Angeles
    • UCLA
    • UCLA Department of Chemical and Biomolecular Engineering

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• PEGylated DNA Helper Molecule Assisted Polyelectrolyte Complex Micelle Formation

  ORAL

  March 17, 2025, 5:12 PM – March 17, 2025, 5:24 PM

  Presenters

  • Sheng Li

    • KAIST

  Authors

  • Sheng Li

    • KAIST

  • Jin Sol Shin

    • KAIST

  • Kwanghee Lee

    • KAIST

  • Weijia Tang

    • KAIST

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• Counterion condensation in polyelectrolyte solutions

  ORAL

  March 17, 2025, 5:24 PM – March 17, 2025, 5:36 PM

  Presenters

  • Carlos G Lopez

    • Penn State University

  Authors

  • Carlos G Lopez

    • Penn State University

  • Takaichi Watanabe

    • Okayama University

  • Atsushi Matsumoto

    • Fukui University

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• Thermodynamics and Dynamics of Telechelic Ionic Associating Polymer

  ORAL

  March 17, 2025, 5:36 PM – March 17, 2025, 5:48 PM

  Presenters

  • Shuyi Xie

    • Texas A&M University College Station

  Authors

  • Shuyi Xie

    • Texas A&M University College Station

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• Investigating the Role of Side Chain Length on the Self-Assembly and Solvation Behavior of Sphere-Rod Amphiphiles: A molecular dynamics study

  ORAL

  March 17, 2025, 5:48 PM – March 17, 2025, 6:00 PM

  Presenters

  • Farzad Toiserkani

    • University of Akron

  Authors

  • Farzad Toiserkani

    • University of Akron

  • YIFAN ZHOU

    • University of Akron

  • Tianbo Liu

    • University of Akron

  • Mesfin Tsige

    • University of Akron

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