Cell Fate Transitions I

Presentations

• Timing the decision to override a checkpoint

  ORAL · Invited

  March 19, 2025, 11:30 AM – March 19, 2025, 12:06 PM

  Presenters

  • Sahand J Rahi

    • École Polytechnique Fédérale de Lausanne

  Authors

  • Sahand J Rahi

    • École Polytechnique Fédérale de Lausanne

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• Shaping fate: geometric methods for cell fate transitions and tissue patterning in stem cells and organoids

  ORAL

  March 19, 2025, 12:06 PM – March 19, 2025, 12:18 PM

  Presenters

  • Dillon Jeffrey Cislo

    • Rockefeller University

  Authors

  • Dillon Jeffrey Cislo

    • Rockefeller University

  • Eric D Siggia

    • Cornell University

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• Integrative Imaging and Machine Learning for Temporal Tracking of Cell Cycle-Resolved Phenotypic Transitions

  ORAL

  March 19, 2025, 12:18 PM – March 19, 2025, 12:30 PM

  Presenters

  • Gaohan Yu

    • University of Pittsburgh

  Authors

  • Gaohan Yu

    • University of Pittsburgh

  • Jianhua Xing

    • University of Pittsburgh

  • Zhiqian Zheng

    • University of Pittsburgh

  • Yong Lu

    • University of Pittsburgh

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• Abstract Withdrawn

  ORAL · Withdrawn

  March 19, 2025, 12:30 PM – March 19, 2025, 12:42 PM

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• Prognostic Value of M1-like and M2-like Tumor-Associated Macrophage Signatures and Their Ratio in Renal Cell Carcinoma

  ORAL

  March 19, 2025, 12:42 PM – March 19, 2025, 12:54 PM

  Presenters

  • Chongming Jiang

    • Terasaki Institute for Biomedical Innovation

  Authors

  • Chongming Jiang

    • Terasaki Institute for Biomedical Innovation

  • Youngsoo Han

    • University of California, Los Angeles

  • Aidan Shen

    • Terasaki Institute for Biomedical Innovation

  • Olamide Adefioye

    • Terasaki Institute for Biomedical Innovation

  • Yangzhi Zhu

    • Terasaki Institute for Biomedical Innovation

  • Xiuying Li

    • Terasaki Institute for Biomedical Innovation

  • Zhaohui Wang

    • Terasaki Institute for Biomedical Innovation

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• Extracting causal gene perturbations from transcriptomic data

  ORAL

  March 19, 2025, 12:54 PM – March 19, 2025, 1:06 PM

  Presenters

  • Benjamin Kuznets-Speck

    • Northwestern University

  Authors

  • Benjamin Kuznets-Speck

    • Northwestern University

  • Yogesh Goyal

    • Northwestern University

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• Membrane mechanics of exo-endocytosis coupling encodes memory for presynaptic neuron short-term plasticity

  ORAL

  March 19, 2025, 1:06 PM – March 19, 2025, 1:18 PM

  Publication: Ogunmowo T, Jing HY, Raychaudhuri S, Kusick GF, Imoto Y, Li S, Itoh K, Chapman ER, Ha TJ, Watanabe S, Liu J. Membrane compression by synaptic vesicle exocytosis triggers ultrafast endocytosis. Nature Communications 2023, May 20; 14 (1): 2888.

  Presenters

  • Jian Liu

    • Johns Hopkins University School of Medicine

  Authors

  • Jian Liu

    • Johns Hopkins University School of Medicine

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• Uncovering underlying physical principles and driving forces of cell differentiation and reprogramming from single-cell transcriptomics

  ORAL

  March 19, 2025, 1:18 PM – March 19, 2025, 1:30 PM

  Publication: Ligang Zhu, Songlin Yan, Kun Zhang, Hong Wang, Xiaona Fang* and Jin Wang*, Uncovering underlying physical principles and driving forces of cell differentiation and reprogramming from single-cell transcriptomics, Proc. Natl. Acad. Sci. 121 (34 ) , e2401540121(2024)

  Presenters

  • Jin Wang

    • Wenzhou Institute and Stony Brook University
    • Stony Brook University (SUNY)

  Authors

  • Jin Wang

    • Wenzhou Institute and Stony Brook University
    • Stony Brook University (SUNY)

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• Performing nonlinear stability analysis for a highly interconnected gene network model

  ORAL

  March 19, 2025, 1:30 PM – March 19, 2025, 1:42 PM

  Presenters

  • Nimasha Samarawickrama

    • University of North Dakota

  Authors

  • Nimasha Samarawickrama

    • University of North Dakota

  • Yen Lee Loh

    • University of North Dakota

  • Manu Manu

    • University of North Dakota

  • Andrea Repele

    • University of North dakota

  • Joanna Handzlik

    • University of North Dakota

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• Physical modeling of embryonic transcriptomes identifies collective modes of gene expression

  ORAL

  March 19, 2025, 1:42 PM – March 19, 2025, 1:54 PM

  Publication: https://doi.org/10.1101/2024.07.26.605398

  Presenters

  • Dominic J Skinner

    • Flatiron Institute

  Authors

  • Dominic J Skinner

    • Flatiron Institute

  • Patrick Lemaire

    • Université de Montpellier

  • Madhav Mani

    • Northwestern University
    • Northwestern

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• Finding signatures of low-dimensional geometric landscapes in high-dimensional cell fate transitions

  ORAL

  March 19, 2025, 1:54 PM – March 19, 2025, 2:06 PM

  Publication: Published: scTOP: physics-inspired order parameters for cellular identification and visualization
  Planned: Finding signatures of low-dimensional geometric landscapes in high-dimensional cell fate transitions

  Presenters

  • Maria Yampolskaya

    • Boston University

  Authors

  • Maria Yampolskaya

    • Boston University

  • Pankaj Mehta

    • Boston University

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• Intrinsic versus extrinsic cellular decision making

  ORAL

  March 19, 2025, 2:06 PM – March 19, 2025, 2:18 PM

  Publication: L. González, B. Han and A. Mugler, Intrinsic versus extrinsic cellular decision making. arXiv preprint arXiv:2410.12081 (2024)

  Presenters

  • Louis Gonzalez

    • University of Pittsburgh

  Authors

  • Louis Gonzalez

    • University of Pittsburgh

  • Bumsoo Han

    • University of Illinois Urbana-Champaign

  • Andrew Mugler

    • University of Pittsburgh

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• Differential motility leads to intestinal organoid budding.

  ORAL

  March 19, 2025, 2:18 PM – March 19, 2025, 2:30 PM

  Presenters

  • Sahil Islam

    • Indian Institute of Technology, Hyderabad

  Authors

  • Sahil Islam

    • Indian Institute of Technology, Hyderabad

  • Suhail Rizvi

    • Indian Institute of Technology Hyderabad

  • L Mahadevan

    • Harvard University

  • Alberto Elosegui-Artola

    • Francis Crick Institute, & King's College London, NW1 1AT, London, UK

  • Anupam Gupta

    • Indian Institute of Technology Hyderabad

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