Physics of Learning and Adaptation II

Presentations

• When is "just right" also "much more than enough"? Surprising lessons on optimality from a bacterium

  Invited-In-person · Invited

  March 18, 2026, 12:00 PM – March 18, 2026, 12:36 PM

  Publication: Teresa W Lo, H James Choi, Dean Huang, and Paul A Wiggins. Noise robustness and metabolic load determine the principles of central dogma regulation. Sci Adv, 10(34):eado3095, Aug 2024.
  H James Choi, Teresa W Lo, Kevin J Cutler, Dean Huang, W Ryan Will, and Paul A Wiggins. Protein overabundance is driven by growth robustness. bioRxiv (Under review at Sci Adv).

  Presenters

  • Paul Wiggins

    • University of Washington

  Authors

  • Paul Wiggins

    • University of Washington

  • James Choi

    • University of Washington

  • Teresa Lo

    • University of Washington

  • Kevin Cutler

  • Dean Huang

    • University of Washington

  • Ryan Will

  View abstract →

• Mechanochemical model for Adaptive Motility in E.coli via Peptidoglycan network training

  Oral-In-person

  March 18, 2026, 12:36 PM – March 18, 2026, 12:48 PM

  Presenters

  • Nada Elmeligy

    • Syracuse University

  Authors

  • Nada Elmeligy

    • Syracuse University

  • Jennifer Schwarz

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• Training elastic network models to change conformation

  Oral-In-person

  March 18, 2026, 12:48 PM – March 18, 2026, 1:00 PM

  Publication: [1] Haliloglu, T., Bahar, I. & Erman, B. (1997). Gaussian dynamics of folded proteins. Physical Review Letters, 79(16)
  [2] Stern, M., Guzman, M., Martins, F., Liu, A. J., &; Balasubramanian, V. (2025). Physical Networks become what they learn. Physical Review Letters, 134(14).
  [3] Guzman, M., Martins, F., Stern, M., & Liu, A. J. (2025). Microscopic imprints of Learned Solutions in tunable networks. Physical Review X, 15(3)

  Presenters

  • Felipe Martins

    • University of Pennsylvania

  Authors

  • Felipe Martins

    • University of Pennsylvania

  • Marcelo Guzmán

    • University of Pennsylvania

  • Andrea Liu

    • University of Pennsylvania

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• Multi-State Allosteric Behavior in Tuned Thermal Mechanical Networks

  Oral-In-person

  March 18, 2026, 1:00 PM – March 18, 2026, 1:12 PM

  Presenters

  • Yue Shang

    • University of Pennsylvania

  Authors

  • Yue Shang

    • University of Pennsylvania

  • Adam Frim

  • Andrea Liu

    • University of Pennsylvania

  • Sidney Nagel

    • University of Chicago

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• Training Stress Patterns in 3D Cellular Packings

  Oral-In-person

  March 18, 2026, 1:12 PM – March 18, 2026, 1:24 PM

  Publication: Training Stress Patterns in 3D Cellular Packings; Shabeeb Ameen, Tao Zhang, J.M. Schwarz (in preparation)

  Presenters

  • Shabeeb Ameen

    • Syracuse University

  Authors

  • Shabeeb Ameen

    • Syracuse University

  • Tao Zhang

    • Shanghai Jiao Tong Univ

  • Jennifer Schwarz

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• Stable memories maintained by local rules require non-local correlations

  Oral-In-person

  March 18, 2026, 1:24 PM – March 18, 2026, 1:36 PM

  Presenters

  • Serena Debesai

    • University of Chicago

  Authors

  • Serena Debesai

    • University of Chicago

  • Martin Falk

    • University of Chicago

  • Arvind Murugan

    • University of Chicago

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• Fluctuating environments reveal principles of rapid structural adaptability

  Oral-In-person

  March 18, 2026, 1:36 PM – March 18, 2026, 1:48 PM

  Presenters

  • Martin Falk

    • University of Chicago

  Authors

  • Martin Falk

    • University of Chicago

  • Christopher Russo

  • Sean Quigley

  • Arvind Murugan

    • University of Chicago

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• Compression-Induced Giant Vortex in a Human Breast Epithelial Spheroid

  Oral-In-person · Withdrawn

  March 18, 2026, 1:48 PM – March 18, 2026, 2:00 PM

  Presenters

  • Young Joon Suh

    • Cornell University

  Authors

  • Young Joon Suh

    • Cornell University

  • Manli Liu

  • Liyang Wang

  • Caleb Takiguchi

  • Yukun Sun

    • Cornell University

  • Jeffrey Segall

  • Nikolaos Bouklas

    • Cornell University

  • Jennifer Schwarz

  • Chris Roh

    • Cornell University

  • Tao Zhang

  • Mingming Wu

    • Cornell University

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• Origin of Resource-Induced Phase Transitions in Biological Information Processing

  Oral-In-person

  March 18, 2026, 2:00 PM – March 18, 2026, 2:12 PM

  Presenters

  • Takehiro Tottori

    • RIKEN Center for Brain Science

  Authors

  • Takehiro Tottori

    • RIKEN Center for Brain Science

  • Tetsuya Kobayashi

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• Trainable computation in many-to-many molecular networks

  Oral-In-person

  March 18, 2026, 2:12 PM – March 18, 2026, 2:24 PM

  Presenters

  • Kristina Trifonova

    • University of Chicago

  Authors

  • Kristina Trifonova

    • University of Chicago

  • Martin Falk

    • University of Chicago

  • Mason Rouches

    • University of Chicago

  • Suriyanarayanan Vaikuntanathan

    • University of Chicago

  • Michael Elowitz

    • Caltech

  • Arvind Murugan

    • University of Chicago

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• Differential dynamic microscopy with light field microscopy for quantifying dynamics in 3D

  Oral-In-person

  March 18, 2026, 2:24 PM – March 18, 2026, 2:36 PM

  Presenters

  • Dylan Gage

    • University of San Diego

  Authors

  • Dylan Gage

    • University of San Diego

  • Gabriel Ambrose

    • University of San Diego

  • Gildardo Martinez

    • University of San Diego

  • Zayda Kellogg

  • Ryan McGorty

    • University of San Diego

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• Disentangling Solvent Nuclear Quantum Effects and Electrostatics in the Carboxylate Vibrational Probe

  Oral-In-person

  March 18, 2026, 2:36 PM – March 18, 2026, 2:48 PM

  Presenters

  • Mojgan Asadi

    • Stanford University

  Authors

  • Mojgan Asadi

    • Stanford University

  • Steven Boxer

  • Thomas Markland

  View abstract →