Physics of Learning and Adaptation II

Presentations

•  When is "just right" also "much more than enough"? Surprising lessons on optimality from a bacterium

  ORAL · Invited

  March 18, 2026, 12:00 PM – March 18, 2026, 12:36 PM

  Publication: Teresa W Lo, H James Choi, Dean Huang, and Paul A Wiggins. Noise robustness and metabolic load determine the principles of central dogma regulation. Sci Adv, 10(34):eado3095, Aug 2024.
  H James Choi, Teresa W Lo, Kevin J Cutler, Dean Huang, W Ryan Will, and Paul A Wiggins. Protein overabundance is driven by growth robustness. bioRxiv (Under review at Sci Adv).

  Presenters

  • Paul Wiggins

    • University of Washington

  Authors

  • Paul Wiggins

    • University of Washington

  • James Choi

    • University of Washington

  • Teresa W Lo

    • University of Washington

  • Kevin Cutler

    • Department of Physics, University of Washington

  • Dean Huang

    • University of Washington

  • Ryan Will

    • Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington 98195, USA

  View abstract →

• Mechanochemical model for Adaptive Motility in E.coli via Peptidoglycan network training

  ORAL

  March 18, 2026, 12:36 PM – March 18, 2026, 12:48 PM

  Presenters

  • Nada Elmeligy

    • Syracuse University

  Authors

  • Nada Elmeligy

    • Syracuse University

  • Jennifer M Schwarz

    • Syracuse University
    • syracuse university

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• Training elastic network models to change conformation

  ORAL

  March 18, 2026, 12:48 PM – March 18, 2026, 1:00 PM

  Publication: [1] Haliloglu, T., Bahar, I. & Erman, B. (1997). Gaussian dynamics of folded proteins. Physical Review Letters, 79(16)
  [2] Stern, M., Guzman, M., Martins, F., Liu, A. J., &; Balasubramanian, V. (2025). Physical Networks become what they learn. Physical Review Letters, 134(14).
  [3] Guzman, M., Martins, F., Stern, M., & Liu, A. J. (2025). Microscopic imprints of Learned Solutions in tunable networks. Physical Review X, 15(3)

  Presenters

  • Felipe Martins

    • University of Pennsylvania

  Authors

  • Felipe Martins

    • University of Pennsylvania

  • Marcelo Guzmán

    • University of Pennsylvania

  • Andrea Jo-Wei Liu

    • University of Pennsylvania

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• Multi-State Allosteric Behavior in Tuned Thermal Mechanical Networks

  ORAL

  March 18, 2026, 1:00 PM – March 18, 2026, 1:12 PM

  Presenters

  • Yue Shang

    • University of Pennsylvania

  Authors

  • Yue Shang

    • University of Pennsylvania

  • Adam Gabriel Frim

    • University of Pennsylvania

  • Andrea Jo-Wei Liu

    • University of Pennsylvania

  • Sidney Robert Nagel

    • University of Chicago

  View abstract →

• Training Stress Patterns in 3D Cellular Packings

  ORAL

  March 18, 2026, 1:12 PM – March 18, 2026, 1:24 PM

  Publication: Training Stress Patterns in 3D Cellular Packings; Shabeeb Ameen, Tao Zhang, J.M. Schwarz (in preparation)

  Presenters

  • Shabeeb Ameen

    • Syracuse University

  Authors

  • Shabeeb Ameen

    • Syracuse University

  • Tao Zhang

    • Shanghai Jiao Tong Univ

  • Jennifer M Schwarz

    • Syracuse University
    • syracuse university

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• Stable memories maintained by local rules require non-local correlations

  ORAL

  March 18, 2026, 1:24 PM – March 18, 2026, 1:36 PM

  Presenters

  • Serena G Debesai

    • University of Chicago

  Authors

  • Serena G Debesai

    • University of Chicago

  • Martin J Falk

    • University of Chicago

  • Arvind Murugan

    • University of Chicago

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• Fluctuating environments reveal principles of rapid structural adaptability

  ORAL

  March 18, 2026, 1:36 PM – March 18, 2026, 1:48 PM

  Presenters

  • Martin J Falk

    • University of Chicago

  Authors

  • Martin J Falk

    • University of Chicago

  • Christopher J Russo

    • University of Chicago

  • Sean Quigley

    • University of Chicago

  • Arvind Murugan

    • University of Chicago

  View abstract →

• Abstract Withdrawn

  ORAL · Withdrawn

  March 18, 2026, 1:48 PM – March 18, 2026, 2:00 PM

  View abstract →

• Origin of Resource-Induced Phase Transitions in Biological Information Processing

  ORAL

  March 18, 2026, 2:00 PM – March 18, 2026, 2:12 PM

  Presenters

  • Takehiro Tottori

    • Laboratory for Neural Computation and Adaptation, RIKEN Center for Brain Science

  Authors

  • Takehiro Tottori

    • Laboratory for Neural Computation and Adaptation, RIKEN Center for Brain Science

  • Tetsuya J Kobayashi

    • Institute of Industrial Science, The University of Tokyo

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• Trainable computation in many-to-many molecular networks

  ORAL

  March 18, 2026, 2:12 PM – March 18, 2026, 2:24 PM

  Presenters

  • Kristina Trifonova

    • University of Chicago

  Authors

  • Kristina Trifonova

    • University of Chicago

  • Martin J Falk

    • University of Chicago

  • Mason N Rouches

    • University of Chicago

  • Suriyanarayanan Vaikuntanathan

    • University of Chicago

  • Michael Elowitz

    • Caltech

  • Arvind Murugan

    • University of Chicago

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• Differential dynamic microscopy with light field microscopy for quantifying dynamics in 3D

  ORAL

  March 18, 2026, 2:24 PM – March 18, 2026, 2:36 PM

  Presenters

  • Dylan Gage

    • University of San Diego

  Authors

  • Dylan Gage

    • University of San Diego

  • Gabriel S Ambrose

    • University of San Diego

  • Gildardo Martinez

    • University of San Diego

  • Zayda Kellogg

    • Bennington College

  • Ryan J. McGorty

    • University of San Diego

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• Disentangling Solvent Nuclear Quantum Effects and Electrostatics in the Carboxylate Vibrational Probe

  ORAL

  March 18, 2026, 2:36 PM – March 18, 2026, 2:48 PM

  Presenters

  • Mojgan Asadi

    • Stanford University

  Authors

  • Mojgan Asadi

    • Stanford University

  • Steven Boxer

    • Stanford University

  • Thomas E Markland

    • Stanford University

  View abstract →