Mechanics of Cells and Tissues II

Presentations

• Active response of metabolically intact isolated nuclei to compression

  ORAL

  March 6, 2024, 9:00 AM – March 6, 2024, 9:12 AM

  Presenters

  • Paul A Janmey

    University of Pennsylvania

  Authors

  • Fitzroy J Byfield

    University of Pennsylvania

  • Alison E Patteson

    Syracuse University

  • Paul A Janmey

    University of Pennsylvania

  View abstract →

• Complex Rheology in Single Cells: compression stiffening but shear softening

  ORAL

  March 6, 2024, 9:12 AM – March 6, 2024, 9:24 AM

  Publication: Actin and vimentin: equal partners in cell mechanics (manuscript in preparation)
  Single cells compression stiffen but shear soften (manuscript in preparation)

  Presenters

  • James P Conboy

    Delft University of Technology

  Authors

  • James P Conboy

    Delft University of Technology

  • Pouyan E Boukany

    Delft University of Technology

  • Gijsje H Koenderink

    Delft University of Technology

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• Stoichiometric Model for the Microtubule-mediated dynamics of centrosome and nucleus

  ORAL

  March 6, 2024, 9:24 AM – March 6, 2024, 9:36 AM

  Presenters

  • Yuan-Nan Young

    New Jersey Institute of Technology

  Authors

  • Yuan-Nan Young

    New Jersey Institute of Technology

  • Reza Farhadifar

    Flatiron Institute

  • Michael J Shelley

    Flatiron Institute (Simons Foundation)

  • Justin Maramuthal

    New Jersey Institute of Technology

  • Libin Liu

    Flatiron Institute

  • Alex Barnett

    Flatiron Institute

  View abstract →

• In situ single-cell mechanics of mouse preimplantation embryos

  ORAL

  March 6, 2024, 9:36 AM – March 6, 2024, 9:48 AM

  Presenters

  • Haiqian Yang

    Massachusetts Institute of Technology MIT

  Authors

  • Haiqian Yang

    Massachusetts Institute of Technology MIT

  • Ehsan Habibi

    Broad Institute of MIT and Harvard

  • Anubhav Sinha

    Broad Institute of MIT and Harvard

  • Aviv Regev

    Broad Institute of MIT and Harvard

  • Fei Chen

    Broad Institute of MIT and Harvard

  • Ming Guo

    Massachusetts Institute of Technology MIT, MIT

  View abstract →

• On the Topology and Dynamics of Breast Cancer Cell Morphologies

  ORAL

  March 6, 2024, 9:48 AM – March 6, 2024, 10:00 AM

  Presenters

  • Christian Cunningham

    Oregon State University

  Authors

  • Christian Cunningham

    Oregon State University

  • Bo Sun

    Oregon State University

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• Cancer Cell Footprinting and Exploration in Micropatterned Fibrinogen Mazes

  ORAL

  March 6, 2024, 10:00 AM – March 6, 2024, 10:12 AM

  Presenters

  • Trevor Reid

    Oregon State University

  Authors

  • Trevor Reid

    Oregon State University

  • Bo Sun

    Oregon State University

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• Deciphering Tumor Heterogeneity in Triple-Negative Breast Cancer: The Crucial Role of Dynamic Cell-Cell and Cell-Matrix Interactions

  ORAL · Invited

  March 6, 2024, 10:12 AM – March 6, 2024, 10:48 AM

  Publication: Rare populations of invasive cells drive progression of heterogeneous tumors
  Leggett SE*, Brennan MC*, Martinez S,Tien J, Nelson CM. (under revision) 2023
  
  
  Mechanophenotyping of 3D multicellular clusters using displacement arrays of rendered tractions.
  Leggett SE, Patel M, Valentin TM, Gamboa L, Khoo AS, Williams EK, Franck C, Wong IY. Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):5655-5663.

  Presenters

  • Susan Leggett

    University of Illinois Urbana-Champaign

  Authors

  • Susan Leggett

    University of Illinois Urbana-Champaign

  • Ian Wong

    Brown University

  • Celeste Nelson

    Princeton University

  • Molly Brennan

    Princeton University

  • Mohak Patel

    Google (Bard)

  • Christian Franck

    University of Wisconsin - Madison

  • Sophia Martinez

    Princeton University

  • Joe Tien

    Boston University

  • Lena Gamboa

    Port Therapeutics

  • Thomas Valentin

    CSEM

  • Amanda Khoo

    Mediar Therapeutics

  • Evelyn K Williams

    Georgia Institute of Technology

  View abstract →

• Fluidization of jammed epithelia by noninvasive carcinoma in a heterogeneous tumor model.

  ORAL

  March 6, 2024, 10:48 AM – March 6, 2024, 11:00 AM

  Presenters

  • Karen Yu

    Columbia University

  Authors

  • Karen Yu

    Columbia University

  • Alex Devanny

    Columbia University

  • Laura Kaufman

    Columbia Univ, Columbia University

  View abstract →

• Modeling Nonlinear Dynamics of Cells in Confinement

  ORAL

  March 6, 2024, 11:00 AM – March 6, 2024, 11:12 AM

  Presenters

  • Pedrom Zadeh

    Johns Hopkins University

  Authors

  • Pedrom Zadeh

    Johns Hopkins University

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• Long-Wavelength Interface Fluctuations Between Different Cell Populations are Suppressed by Friction

  ORAL

  March 6, 2024, 11:12 AM – March 6, 2024, 11:24 AM

  Presenters

  • Haicen Yue

    University of Vermont

  Authors

  • Haicen Yue

    University of Vermont

  • Daniel M Sussman

    Emory University

  View abstract →

• Model of cell-cell adhesions as cytockeleton-to-cytoskeleton linkers

  ORAL

  March 6, 2024, 11:24 AM – March 6, 2024, 11:36 AM

  Publication: None

  Presenters

  • XinXin Du

    Simons Foundation Flatiron Institute

  Authors

  • XinXin Du

    Simons Foundation Flatiron Institute

  • Michael J Shelley

    Flatiron Institute (Simons Foundation)

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• Microrheology of suspended cells using optical traps

  ORAL

  March 6, 2024, 11:36 AM – March 6, 2024, 11:48 AM

  Presenters

  • Mingru Li

    Duke University

  Authors

  • Mingru Li

    Duke University

  • Paul A Janmey

    University of Pennsylvania

  • Siyan He

    Duke University

  • Brenton D Hoffman

    Duke University

  • Fitzroy J Byfield

    University of Pennsylvania

  • Christoph F Schmidt

    Duke University

  View abstract →

• Combinatorial role of mechano-chemical cues in cell mechanics and state transitions

  ORAL

  March 6, 2024, 11:48 AM – March 6, 2024, 12:00 PM

  Presenters

  • M Sreepadmanabh

    National Centre for Biological Sciences, National Centre for Biological Sciences-TIFR

  Authors

  • M Sreepadmanabh

    National Centre for Biological Sciences, National Centre for Biological Sciences-TIFR

  • Ashitha B Arun

    National Center for Biological Sciences

  • Nandhu K Babu

    National Centre for Biological Sciences

  • Nivedita Chaudhary

    Institute for Stem Cell Science and Regenerative Medicine

  • Dasaradhi Palakodeti

    Institute for Stem Cell Science and Regenerative Medicine

  • Tapomoy Bhattacharjee

    Tata Institute of Fundamental Research - NCBS, National Centre for Biological Sciences, National Centre for Biological Sciences-TIFR

  View abstract →